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Merck
CN

481432

Sigma-Aldrich

溴化氰

99.995% trace metals basis

别名:

氰化溴

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About This Item

线性分子式:
BrCN
CAS号:
分子量:
105.92
Beilstein:
1697296
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽密度

3.65 (vs air)

质量水平

蒸汽压

100 mmHg ( 22.6 °C)

检测方案

99.995% trace metals basis

bp

61-62 °C (lit.)

mp

50-53 °C (lit.)

储存温度

2-8°C

SMILES字符串

BrC#N

InChI

1S/CBrN/c2-1-3

InChI key

ATDGTVJJHBUTRL-UHFFFAOYSA-N

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一般描述

Cyanogen bromide (CNBr) is a halogen halide. Its utility as a condensing agent during chemical ligation of oligodeoxyribonucleotides has been reported. Its threshold photoelectron (TPE) spectrum has been recorded under high resolution. The cryopolymerization of CNBr on irradiation has been investigated.

应用

与 C60P 5Cl 反应生成新型苯代异喹啉并[3′,4′:1,2][60]富勒烯。
Cyanogen bromide may be used:
  • To activate polysaccharides for coupling with erythrocytes.
  • As an oxidizing agent in the urine thaimine assay.
  • In the preparation of 2-amino-5-(2′-thienyl)-1,3,4-oxadiazole.

警示用语:

Danger

危险分类

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B

补充剂危害

WGK

WGK 3

闪点(°F)

>149.0 °F

闪点(°C)

> 65 °C

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges

法规信息

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N I Sokolova et al.
FEBS letters, 232(1), 153-155 (1988-05-09)
Cyanogen bromide was found to condense oligodeoxyribonucleotides on a complementary template in aqueous solution. Optimum conditions for this vigorous and effective reaction were developed. CNBr proved to be useful for incorporation of phosphoramidate or pyrophosphate internucleotide bonds in DNA duplexes.
Threshold photoelectron spectroscopy of cyanogen bromide.
Yencha AJ, et al.
Chemical Physics Letters, 392(1), 202-208 (2004)
Abdul-Sada, A.K. et al.
Chemical Communications (Cambridge, England), 307-307 (1998)
Oxadiazole: a biologically important heterocycle.
Somani RR and Shirodkar PY.
Der Pharma Chemica, 1(1), 130-140 (2009)
Low-temperature radiation polymerization of cyanogen bromide.
Kichigina GA, et al.
Mendeleev Communications, 8(4), 159-160 (1998)

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