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Merck
CN

479950

醛缩酶抗体 38C2,鼠催化性单克隆抗体

average Mw ~150,000, powder (Lyophilized, contains pbs)

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UNSPSC Code:
12352200
MDL number:
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antibody product type

primary antibodies

form

powder (Lyophilized, contains pbs)

mol wt

average Mw ~150,000

storage temp.

−20°C

Application

用于羟醛缩合的生物催化剂,特别是脂肪酮到醛的 si-面加成。抗体 38C2 可催化羟醛、交叉羟醛、逆羟醛、β-酮酸脱羧、自羟醛以及 Robinson 环化反应。该生物催化剂适用于具有不同物化特性的多种底物。

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说明

  • 10 mg

  • 5-6.5 mg

  • antibody 10 mg

  • phosphate buffer salts 5-6.5 mg

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R A Lerner et al.
Science (New York, N.Y.), 252(5006), 659-667 (1991-05-03)
Immunochemistry has historically focused on the nature of antigenicity and antibody-antigen recognition. However, in the last 5 years, the field of immunochemistry has taken a new direction. With the aid of mechanistic and synthetic chemistry, the vast network of molecules
J Wagner et al.
Science (New York, N.Y.), 270(5243), 1797-1800 (1995-12-15)
Antibodies that catalyze the aldol reaction, a basic carbon-carbon bond-forming reaction, have been generated. The mechanism for antibody catalysis of this reaction mimics that used by natural class I aldolase enzymes. Immunization with a reactive compound covalently trapped a Lys
P Wirsching et al.
Science (New York, N.Y.), 270(5243), 1775-1782 (1995-12-15)
For almost 200 years inert antigens have been used for initiating the process of immunization. A procedure is now described in which the antigen used is so highly reactive that a chemical reaction occurs in the antibody combining site during

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