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479179

Sigma-Aldrich

(S)-(-)-4-羟基-2-吡咯烷酮

97%

别名:

(S)-β-羟基-γ-丁内酰胺

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1 MG
¥637.75
5 MG
¥2,192.72

¥637.75

国内现货，预计发货时间2025年4月16日详情

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1 MG
¥637.75
5 MG
¥2,192.72

About This Item

经验公式（希尔记法）:
C4H7NO2
CAS号:
68108-18-9
分子量:
101.10
Beilstein:
1524192
MDL编号:
MFCD00273370
UNSPSC代码:
12352005
PubChem化学物质编号:
24871604
NACRES:
NA.22

¥637.75

国内现货，预计发货时间2025年4月16日详情

获取大包装报价

方案

97%

旋光性

[α]23/D −43°, c = 1 in ethanol

mp

156-159 °C (lit.)

官能团

hydroxyl

SMILES字符串

O[C@@H]1CNC(=O)C1

InChI

1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m0/s1

InChI key

IOGISYQVOGVIEU-VKHMYHEASA-N

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EHU067331EHU092821EHU114811
MISSION® esiRNA targeting human TRIM29

EHU087831

MISSION® esiRNA

MISSION® esiRNA targeting human TRIM28

EHU067331

MISSION® esiRNA

MISSION® esiRNA targeting human TRIM69

EHU092821

MISSION® esiRNA

MISSION® esiRNA targeting human TRIM26

EHU114811

MISSION® esiRNA

esiRNA cDNA target sequence

TCATGGATGCTCTGGATGAGAGAGCCAAGGTGCTGCATGAGGACAAGCAGACCCGGGAGCAGCTGCATAGCATCAGCGACTCTGTGTTGTTTCTGCAGGAATTTGGTGCATTGATGAGCAATTACTCTCTCCCCCCACCCCTGCCCACCTATCATGTCCTGCTGGAGGGGGAGGGCCTGGGACAGTCACTAGGCAACTTCAAGGACGACCTGCTCAATGTATGCATGCGCCACGTTGAGAAGATGTGCAAGGCGGACCTGAGCCGTAACTTCATTGAGAGGAACCACATGGAGAACGGTGGTGACCATCGCTATGTGAACAACTACACGAACAGCTTCGGGGGTGAGTGGAGTGCACCGGACACCATGAAGAGATACTCCATGTACCTGACACCCAAAGGTGGGGTCCGGACATCATACCAGCCCTCGTC

esiRNA cDNA target sequence

CACAAGGACCACCAGTACCAGTTCTTAGAGGATGCAGTGAGGAACCAGCGCAAGCTCCTGGCCTCACTGGTGAAGCGCCTTGGGGACAAACATGCAACATTGCAGAAGAGCACCAAGGAGGTTCGCAGCTCAATCCGCCAGGTGTCTGACGTACAGAAGCGTGTGCAAGTGGATGTCAAGATGGCCATCCTGCAGATCATGAAGGAGCTGAATAAGCGGGGCCGTGTGCTGGTCAATGATGCCCAGAAGGTGACTGAGGGGCAGCAGGAGCGCCTGGAGCGGCAGCACTGGACCATGACCAAGATCCAGAAGCACCAGGAGCACATTCTGCGCTTTGCCTCTTGGGCTCTGGAGAGTGACAACAACACAGCCCTTTTGCTTTCTAAGAAGTTGATCTACTTCCAGCTGCACCG

esiRNA cDNA target sequence

CGTCTGGCATGGTGACATTAAGAAGATAATGCCTGATGATCCTGAGAGGTTTGACTCAAGTGTGGCTGTACTGGGCTCAAGAGGCTTCACCTCTGGAAAGTGGTACTGGGAAGTAGAAGTAGCAAAGAAGACAAAATGGACAGTTGGAGTTGTCAGAGAATCCATCATTCGGAAGGGCAGCTGTCCTCTAACTCCTGAGCAAGGATTCTGGCTTTTAAGACTAAGGAACCAAACTGATCTAAAGGCTCTGGATTTGCCTTCTTTCAGTCTGACACTGACTAACAACCTCGACAAGGTGGGCATATACCTGGATTATGAAGGAGGACAGTTGTCCTTCTACAATGCTAAAACCATGACTCACATTTACACCTTCAGTAACACTTTCATGGAGAAACTTTATCCCTACTTCTGCCCCTGCCTTAAT

esiRNA cDNA target sequence

CAGCGCATATCATCTCATGGGGTCCAGAGTGGAGTCCAGGCTTCTCTGAAACCAGGGCTGAGCATATTTCCATAGCCAAGGAGGTGGGACTCCCTGGAGCTATCTGTGGTCTTAGGGAAGGATCCAGACATACACGGCTTTGGGGTACAAGCTGTGATCACTGATCAATAAATTATCTCTAGATTGGTCCTTGTGAGGGGAGTTTTAAGAATCCAGAACATCTTGCTCTTGATCAGCACATCCAAAAACACCAAGACAAACATCCAGTGGAGCAGAACCTCTCCTGCCTCGGGAGTTCTGACCGGGTTCCCCAGCAGGGTGTTAAGCCTCTGTCTCTGGCCCTACCAGCATCCAGGTTCCACTTTCCTAGGAGAGAGTGGAGATGGGAAGACAGGGAAAGGAAGG

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

Gene Information

human ... TRIM29(23650), TRIM29(23650)

Gene Information

human ... TRIM28(10155), TRIM28(10155)

Gene Information

human ... TRIM69(140691), TRIM69(140691)

Gene Information

human ... TRIM26(7726), TRIM26(7726)

NCBI accession no.

NM_012101

NCBI accession no.

NM_005762

NCBI accession no.

NM_080745

NCBI accession no.

NM_003449

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

一般描述

4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine.[1]

应用

(S)-(−)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:
  • Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.[2]
  • Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.[3]

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险声明

H302,H318

危险分类

Acute Tox. 4 Oral - Eye Dam. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    MKBS0173V
    MKBH7283V
    MKBF0099V
    MKAA2709
    04015EJ

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    A Photochemical Two-Step Formal [5+ 2] Cycloaddition: A Condensation-Ring-Expansion Approach to Substituted Azepanes
    Thullen SM, et al.
    Synlett, 28(20), 2755-2758 (2017)
    Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp. KORDI-3973
    Shin HJ, et al.
    Phytochemistry, 69(12), 2363-2366 (2008)
    First synthesis of pyrrolo [1, 2: 1′, 2′] azepino [5, 6-b] indole derivatives
    Perron J, et al.
    Tetrahedron Letters, 44(35), 6553-6556 (2003)
    G Di Silvestro et al.
    Journal of pharmaceutical sciences, 82(7), 758-760 (1993-07-01)
    The phase diagram of (R)- and (S)-4-hydroxy-2-pyrrolidone presents a conglomerate in the racemic mixture. The enthalpy of melting extrapolated by the Schröder-van Laar-Le Chatelier equation [change in enthalpy (delta H) = 28410 J/mol; melting temperature (TA) = 429.9 K; solidus

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