drug control
Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
refractive index
n20/D 1.561 (lit.)
density
1.024 g/mL at 25 °C (lit.)
InChI key
LMHHFZAXSANGGM-UHFFFAOYSA-N
InChI
1S/C9H11N/c10-9-5-7-3-1-2-4-8(7)6-9/h1-4,9H,5-6,10H2
SMILES string
NC1Cc2ccccc2C1
assay
97%
General description
2-Aminoindan (2-Aminoindane) is an analog of amphetamine. It shows a potential bronchodilator and analgesic effect. The impact of the intramolecular N-H···Π hydrogen bonding on the conformations of 2-Al has been analyzed.
Application
2-Aminoindan may be used to prepare trans-(1S,2S)-2-amino-1-indanol via hydroxylation using dopamine β-hydroxylase (DBH) enzyme. It may be used to synthesize 2-amino-4-chloro-6-(2-aminoindanyl)-1,3,5-triazine.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
监管及禁止进口产品
此项目有
Enzymatic Hydroxylation by Dopamine β-Hydroxylase.
Mitrochkine AA, et al.
European Journal of Organic Chemistry, 1998(6), 1171-1176 (1998)
Hiroshi Iga et al.
The journal of physical chemistry. A, 111(27), 5981-5987 (2007-06-19)
Laser-induced fluorescence (LIF), dispersed fluorescence (DF), mass-resolved one-color resonance enhanced two-photon ionization (RE2PI) and UV-UV hole-burning spectra of 2-aminoindan (2-AI) were measured in a supersonic jet. The hole-burning spectra demonstrated that the congested vibronic structures observed in the LIF excitation
Adam L Halberstadt et al.
Psychopharmacology, 236(3), 989-999 (2019-03-25)
Over the last decade, many new psychostimulant analogues have appeared on the recreational drug market and most are derivatives of amphetamine or cathinone. Another class of designer drugs is derived from the 2-aminoindan structural template. Several members of this class
J G Cannon et al.
Journal of medicinal chemistry, 23(7), 745-749 (1980-07-01)
Three series of bicyclic, semirigid congeners of beta-phenethylamine have been prepared for evaluation of the effect of ring size (and of concomitant conformational variation) on biological activity in a variety of assays for adrenergic and dopaminergic actions. Pharmacologic activity was
P J Hajduk et al.
Journal of medicinal chemistry, 42(19), 3852-3859 (1999-10-03)
The Erm family of methyltransferases confers resistance to the macrolide-lincosamide-streptogramin type B (MLS) antibiotics through the methylation of 23S ribosomal RNA. Upon the methylation of RNA, the MLS antibiotics lose their ability to bind to the ribosome and exhibit their
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持