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Merck
CN

477567

Sigma-Aldrich

5,10,15,20-四(4-羟基苯基)-21H,23H-卟吩

Dye content 95 %

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经验公式(希尔记法):
C44H30N4O4
CAS号:
分子量:
678.73
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

形式

powder

质量水平

组成

Dye content, 95%

mp

>300 °C (lit.)

λmax

421 nm

ε (消光系数)

≥285000 at 417-423 nm in methanol at 0.001 g/L

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

Oc1ccc(cc1)-c2c3ccc(n3)c(-c4ccc(O)cc4)c5ccc([nH]5)c(-c6ccc(O)cc6)c7ccc(n7)c(-c8ccc(O)cc8)c9ccc2[nH]9

InChI

1S/C44H30N4O4/c49-29-9-1-25(2-10-29)41-33-17-19-35(45-33)42(26-3-11-30(50)12-4-26)37-21-23-39(47-37)44(28-7-15-32(52)16-8-28)40-24-22-38(48-40)43(36-20-18-34(41)46-36)27-5-13-31(51)14-6-27/h1-24,45,48-52H/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-

InChI key

VFHDWGAEEDVVPD-LWQDQPMZSA-N

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一般描述

5,10,15,20-四(4-羟基苯基)-21H,23H-卟吩(TPPOH, 2H-OHTPP)是一种非手性卟啉衍生物。

应用

它可被用于制备基于卟啉的基质用于通过基质辅助激光解吸/电离(MALDI)质谱进行水溶性维生素的检测。它还可被用于制备5,10,15,20-四(4-聚乙烯氧基)苯基)卟啉。插入了2H-OHTPP的纳米多孔二氧化硅赋予了其气体敏感性,可用于通过表面等离子体共振检测NO2

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Kinga Nawalany et al.
International journal of pharmaceutics, 430(1-2), 129-140 (2012-04-25)
Photosensitizing properties of 5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin (p-THPP) functionalized by covalent attachment of one chain of poly(ethylene glycol) (PEG) with a molecular weight of 350, 2000, or 5000 Da (p-THPP-PEG(350), p-THPP-PEG(2000), p-THPP-PEG(5000)) were studied in vitro. Dark and photo cytotoxicity of these photosensitizers
Kinga Nawalany et al.
The journal of physical chemistry. B, 112(39), 12231-12239 (2008-09-09)
5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin was functionalized by covalent attachment of poly(ethylene glycol) (PEG) chains of various molecular weights, 350, 2000, and 5000 Da. The properties of PEG-functionalized tetraarylporphyrins in aqueous solution and their interactions with liposomes have been studied. Electronic absorption spectroscopy, dynamic
F Fischer et al.
Clinica chimica acta; international journal of clinical chemistry, 274(1), 89-104 (1998-07-29)
Uric acid a known singlet oxygen scavenger, was investigated as a chemical dosimeter in physiological aqueous solution for use in photodynamic therapy. The uric acid test takes the decrease in uric acid (UA) absorbance at 293 nm after laser light
Detection of water?soluble vitamins by matrix?assisted laser desorption/ionization time?of?flight mass spectrometry using porphyrin matrices.
Chen YT and Ling YC
Journal of Mass Spectrometry : Jms, 37(7), 716-730 (2002)
Yvette Niamien Konan et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 55(1), 115-124 (2003-01-29)
A photosensitizer, meso-tetra(4-hydroxyphenyl)porphyrin, was incorporated into sub-150 nm nanoparticles using the emulsification-diffusion technique in order to perform sterilization by filtration using 0.22 microm membranes. The three selected polyesters (poly(D,L-lactide-co-glycolide), (50:50 PLGA, 75:25 PLGA) and poly(D,L-lactide (PLA)) for the nanoparticle production

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