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Merck
CN

477222

Sigma-Aldrich

4-氯苯胺

purified by sublimation, ≥99%

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别名:
1-Amino-4-chlorobenzene, 4-Chlorophenylamine, p-Chloroaniline
线性分子式:
ClC6H4NH2
CAS号:
分子量:
127.57
Beilstein:
471359
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽密度

4.4 (vs air)

质量水平

蒸汽压

0.15 mmHg ( 25 °C)

检测方案

≥99%

形式

crystals
powder
solid

纯化方式

sublimation

bp

232 °C (lit.)

mp

67-70 °C (lit.)

SMILES字符串

Nc1ccc(Cl)cc1

InChI

1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2

InChI key

QSNSCYSYFYORTR-UHFFFAOYSA-N

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一般描述

4-氯苯胺(4-CLA)是一种氯化芳香胺,在苯脲和苯氨基甲酸酯的微生物分解过程中作为中间体形成。已经报告了在含有氧化还原酶的水溶液中通过4-CLA与愈创木酚的聚合形成各种低聚物。4-CLA通过土壤真菌尖孢镰刀菌的氧化而分解。

应用

4-氯苯胺可被用于合成:
  • 4-氯亚硝基苯
  • 2-溴-4-氯苯胺
  • 2,6-二溴-4-氯苯胺

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Skin Sens. 1

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品

分析证书(COA)

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The action of chloride peroxidase on 4-chloroaniline. N-oxidation and ring halogenation.
Corbett MD, et al.
The Biochemical Journal, 187(3), 893-903 (1980)
Oxidative co-oligomerization of guaiacol and 4-chloroaniline.
Simmons KE, et al.
Environmental Science & Technology, 23(1), 115-121 (1989)
M D Corbett et al.
The Biochemical journal, 175(2), 353-360 (1978-11-01)
The incubation of 4-chloroaniline with chloroperoxidase and H2O2 resulted in a rapid formation of 4-chloronitrosobenzene. This enzymic oxidation displayed a pH optimum at 4.4 with a Km of 8.1x10(-4)M and catalytic-centre activity of 312. The initial rate of the reaction
Microbial oxidation of 4-chloroaniline.
D D Kaufman et al.
Journal of agricultural and food chemistry, 21(1), 127-132 (1973-01-01)
Shashikala Krishnamurthy et al.
Journal of endodontics, 36(7), 1154-1157 (2010-07-16)
The purpose of this study was (1) to evaluate maximum thickness the and chemical composition of the precipitate formed between sodium hypochlorite (NaOCl) and chlorhexidine (CHX) and (2) to evaluate effectiveness of absolute alcohol to remove residual NaOCl and thereby

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