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质量水平
方案
≥95.0% (sum of enantiomers, HPLC)
旋光性
[α]20/D +16.0±2°, c = 1% in THF
反应适用性
reaction type: Fmoc solid-phase peptide synthesis
mp
170-173 °C (lit.)
应用
peptide synthesis
官能团
Fmoc
储存温度
2-8°C
SMILES字符串
OC(=O)[C@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46
InChI
1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1
InChI key
KLBPUVPNPAJWHZ-UMSFTDKQSA-N
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一般描述
Fmoc-Cys(Trt)-OH是Fmoc固相肽合成中常用的氨基酸。
应用
Fmoc-Cys(Trt)-OH是一种N末端保护的半胱氨酸衍生物,可用于肽合成。一些例子包括:
- 合成单官能和双官能化铂(IV)络合物以靶向血管生成肿瘤脉管系统。
- 通过固相合成将肽酰肼作为硫酯替代物进行天然化学连接来合成蛋白质。
- 通过将还原糖与肽的半胱氨酸残基缀合来合成糖结合物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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