所有图片(1)
About This Item
经验公式(希尔记法):
C21H23NO4
CAS号:
分子量:
353.41
Beilstein:
2178254
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
推荐产品
质量水平
方案
≥97.0%
旋光性
[α]20/D −25±2°, c = 1% in DMF
反应适用性
reaction type: C-H Activation
reaction type: Fmoc solid-phase peptide synthesis
reagent type: ligand
reaction type: Peptide Synthesis
mp
152-156 °C (lit.)
152-156 °C
应用
peptide synthesis
官能团
Fmoc
amine
carboxylic acid
储存温度
2-8°C
SMILES字符串
CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
InChI
1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m0/s1
InChI key
CBPJQFCAFFNICX-IBGZPJMESA-N
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应用
Fmoc-Leu-OH可用作合成反应剂:
- 通过与功能化α-氨基酸盐酸盐反应合成寡肽。
- 环酯Sansalvamide A,这是在海洋真菌中发现的一种天然产物。
- Streptocidin A−D,放线菌Tü 6071中天然存在的十肽抗生素。
- 酰基二肽酰胺,可用于化妆品应用。
生化/生理作用
可诱导胰岛素敏感化,但不能诱导脂肪生成的 PPARγ 配体。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Lee Y and Silverman RB
Organic Letters, 2(23), 3743-3746 (2000)
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Organic Letters, 20(3), 612-615 (2018)
Facile solid-phase synthesis of cyclic decapeptide antibiotic streptocidins A-D
Qin C, et al.
Tetrahedron Letters, 45(1), 217-220 (2004)
Markus Beck Erlach et al.
Journal of biomolecular NMR, 69(2), 53-67 (2017-09-16)
For evaluating the pressure responses of folded as well as intrinsically unfolded proteins detectable by NMR spectroscopy the availability of data from well-defined model systems is indispensable. In this work we report the pressure dependence of
Synthesis and Evaluation of Coumaroyl Dipeptide Amide as Potential Whitening Agents
Lee H-S, et al.
Bull. Korean Chem. Soc., 34(10), 3017-3021 (2013)
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