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About This Item
经验公式（希尔记法）:
C17H15NO4
CAS号:
分子量:
297.31
Beilstein:
2163967
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
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质量水平
方案
≥98.0% (T)
表单
powder
反应适用性
reaction type: Fmoc solid-phase peptide synthesis
mp
174-175 °C (lit.)
174-178 °C
应用
peptide synthesis
官能团
Fmoc
储存温度
2-8°C
SMILES字符串
OC(=O)CNC(=O)OCC1c2ccccc2-c3ccccc13
InChI
1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20)
InChI key
NDKDFTQNXLHCGO-UHFFFAOYSA-N
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应用
- Efficient Fmoc-Protected Amino Ester Hydrolysis Using Green Calcium (II) Iodide as a Protective Agent：研究在Fmoc-保护氨基酯的水解反应中采用环境友好的碘化钙，提高反应效率和可持续性(R Binette, M Desgagné, C Theaud, PL Boudreault - Molecules, 2022)。文章链接。
- α/β-Chimera peptide synthesis with cyclic β-sugar amino acids: the efficient coupling protocol：研究采用环β-糖氨基酸更好地合成α/β-嵌合肽，说明在药物化学的多肽设计中具有重要应用潜力(A Nagy, V Goldschmidt Gőz, I Pintér, V Farkas - Amino acids, 2019)。文章链接。
- MS, CD, and FT-IR characterization of five newly synthesized histidine-containing Ala-and Gly-based peptides：详细鉴定了新的含组氨酸多肽，说明对肽类药物开发有重要意义的技术(M Murariu, L Ion, CI Ciobanu, BA Petre - Rev. Roum Chem., 2017)。文章链接。
- Efficient method for the concentration determination of fmoc groups incorporated in the core-shell materials by Fmoc–glycine：详细说明了测定核壳材料中fmoc基团浓度的高效方法，对于先进功能材料的设计具有重要意义(E Szczepańska, B Grobelna, J Ryl, A Kulpa - Molecules, 2020)。文章链接。
- Circular aqueous fmoc/t‐bu solid‐phase peptide synthesis：探索了固相多肽合成的循环水相新方法，可能提供了更高效环保的肽合成方法(J Pawlas, JH Rasmussen - ChemSusChem, 2021)。文章链接。
其他说明
糖类β-糖胺的fmoc-甘氨酸偶联，可用于低聚糖的分馏和新糖结合物的形成。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Methyl-triclosan (MTCS), as a biodegradation product from antibacterial triclosan (TCS), has been detected in water catchments, and it has also been verified to accumulate in biota due to its hydrophobicity. There is a lack, however, of toxicity studies on MTCS
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L Noronha-Blob et al.
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