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经验公式(希尔记法):
C28H29NO5
化学文摘社编号:
分子量:
459.53
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
276-262-7
MDL number:
Beilstein/REAXYS Number:
4216652
产品名称
Fmoc-Tyr(tBu)-OH, ≥98.0% (HPLC)
InChI key
JAUKCFULLJFBFN-VWLOTQADSA-N
InChI
1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m0/s1
SMILES string
CC(C)(C)Oc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)cc1
assay
≥98.0% (HPLC)
form
powder
optical activity
[α]20/D −29±2°, c = 1% in DMF
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
mp
153-156 °C (lit.)
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
Quality Level
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Application
Fmoc-Tyr(tBu)-OH可用于通过水中固相反应合成亮氨酸-脑啡肽酰胺(Leu-Enkephalin Amide)。也用于合成氨基酸衍生物,例如Fmoc-Tyr-OAllyl。
General description
Fmoc-Tyr(tBu)-OH也称为Fmoc-O-叔丁基-L-酪氨酸,通常用于Fmoc固相法肽合成。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Chembiochem : a European journal of chemical biology, 17(24), 2353-2360 (2016-10-28)
We present the design, synthesis, and characterization of a novel photocaged glutamine derivative (modified on the side chain of glutamine), and describe its use in enhancing peptide stability and solubility. Our results demonstrate that this approach can be used to
Chloé Guilbaud-Chéreau et al.
ACS applied materials & interfaces, 11(14), 13147-13157 (2019-03-14)
Molecular gels formed by the self-assembly of low-molecular-weight gelators have received increasing interest because of their potential applications in drug delivery. In particular, the ability of peptides and amino acids to spontaneously self-assemble into three-dimensional fibrous network has been exploited
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