47619
芴甲氧羰基-O-叔丁基-L-丝氨酸
≥98.0% (HPLC), for peptide synthesis
别名:
Fmoc-O-叔丁基-L-丝氨酸
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选择尺寸
关于此项目
经验公式（希尔记法）:
C22H25NO5
化学文摘社编号:
分子量:
383.44
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
276-260-6
MDL number:
Beilstein/REAXYS Number:
3632013
产品名称
芴甲氧羰基-O-叔丁基-L-丝氨酸, ≥98.0% (HPLC)
InChI key
REITVGIIZHFVGU-IBGZPJMESA-N
InChI
1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
SMILES string
CC(C)(C)OC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
assay
≥98.0% (HPLC)
form
powder
optical activity
[α]20/D +25.5±1°, c = 1% in ethyl acetate
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
Quality Level
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Application
FMOC-O-叔丁基-L-丝氨酸是用于多肽合成的 N-末端保护试剂。一些已报道的应用实例有：
- 通过化学选择性丝氨酸连接的环化反应，对抗生素达托霉素进行全合成。
- 使用反复五氟苯酯介导的片段缩合制备MUC1，一种T细胞辅助多肽。
- 泛素和双泛素的线性固相多肽合成。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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