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质量水平
检测方案
95%
mp
>350 °C (lit.)
SMILES字符串
Nc1nc(Br)c2nc[nH]c2n1
InChI
1S/C5H4BrN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)
InChI key
HPGBGNVPUMCKPM-UHFFFAOYSA-N
一般描述
2-Amino-6-bromopurine is a 2-amino-6-halogenopurine. It can be synthesized by reaction between 2-amino-6-chloropurine and KX (X=Br). It has been reported to be a substrate for the adenine deaminase. Orientations of 2-amino-6-bromopurine (ABPu) in the docking conformations of guanine riboswitch complexed with ABPu have been analyzed.
Synthesis of Some Biologically Active Halogenopurines.
Hu YL, et al.
J. Korean Chem. Soc., 54(4), 429-436 (2010)
Theoretical studies on the interaction of guanine riboswitch with guanine and its closest analogues.
Ling B, et al.
Molecular Simulations, 36(12), 929-938 (2010)
D A Jankowska et al.
Journal of applied microbiology, 115(5), 1134-1146 (2013-08-02)
Construction of a transgenic Arxula adeninivorans strain that produces a high concentration of adenine deaminase and investigation into the application of the enzyme in the production of food with low purine content. The A. adeninivorans AADA gene, encoding adenine deaminase
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