47309
Fmoc-D-Trp(Boc)-OH
≥95.0% (HPLC)
别名:
Nα-芴甲氧羰基-N(in)-叔丁氧羰基-D-色氨酸
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关于此项目
经验公式（希尔记法）:
C31H30N2O6
化学文摘社编号:
分子量:
526.58
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
7062970
产品名称
Fmoc-D-Trp(Boc)-OH, ≥95.0% (HPLC)
InChI
1S/C31H30N2O6/c1-31(2,3)39-30(37)33-17-19(20-10-8-9-15-27(20)33)16-26(28(34)35)32-29(36)38-18-25-23-13-6-4-11-21(23)22-12-5-7-14-24(22)25/h4-15,17,25-26H,16,18H2,1-3H3,(H,32,36)(H,34,35)/t26-/m1/s1
SMILES string
CC(C)(C)OC(=O)n1cc(C[C@@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)c5ccccc15
InChI key
ADOHASQZJSJZBT-AREMUKBSSA-N
assay
≥95.0% (HPLC)
form
solid
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
application(s)
peptide synthesis
functional group
Boc
Fmoc
storage temp.
2-8°C
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Fayçal Touti et al.
Nature chemical biology, 15(4), 410-418 (2019-03-20)
The use of competitive inhibitors to disrupt protein-protein interactions (PPIs) holds great promise for the treatment of disease. However, the discovery of high-affinity inhibitors can be a challenge. Here we report a platform for improving the affinity of peptide-based PPI
Ngoc-Duc Doan et al.
Journal of peptide science : an official publication of the European Peptide Society, 21(5), 387-391 (2014-11-18)
The solid-phase synthesis of azapeptides possessing a C-terminal aza-residue has been accomplished by a protocol featuring regioselective alkylation of benzhydrylidene-aza-glycinamide and illustrated by the syntheses of [aza-Lys(6)] growth-hormone-releasing peptide-6 analogs.
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