所有图片(1)
About This Item
线性分子式:
(CH3)2CHCH(NH2)P(O)(OH)2
CAS号:
分子量:
153.12
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
98%
旋光性
[α]20/D +1.0°, c = 1 in 1 M NaOH
mp
272-277 °C (lit.)
官能团
amine
SMILES字符串
CC(C)[C@H](N)P(O)(O)=O
InChI
1S/C4H12NO3P/c1-3(2)4(5)9(6,7)8/h3-4H,5H2,1-2H3,(H2,6,7,8)/t4-/m1/s1
InChI key
DGSLPJDIFKVSIB-SCSAIBSYSA-N
一般描述
The enantiodiscrimination of (1R)-(+)-(1-amino-2-methylpropyl)phosphonic acid from its enantiomer in the gas-phase can be done using ESI-MS-CID technique. [electrospray ionization-mass spectrometric detection-collision induced dissociation]
应用
作为生物体系中氨基羧酸的具有吸引力的替代品。具有备受关注的多种有用属性，如用作肽类似物、 抗病毒试剂 半抗原，用于生成催化抗体、 酶抑制剂、 强效抗生素、 除草剂和农药。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Enantiodiscrimination of chiral a-aminophosphonic acids by mass spectrometry.
Paladini A, et al.
Chirality, 13(10), 707-711 (2001)
Nour Z Atwany et al.
Biology, 9(8) (2020-08-13)
Regulatory T cells (Tregs) are key players in the regulation of inflammatory responses. In this study, two natural molecules, namely, sparteine sulfate (SS) and harpagoside (Harp), were investigated for their ability to induce Tregs in human peripheral blood mononuclear cells
Camp, N.P. et al.
Bioorganic & Medicinal Chemistry Letters, 2, 1047-1047 (1992)
M C Allen et al.
Journal of medicinal chemistry, 32(7), 1652-1661 (1989-07-01)
The synthesis of five amino phosphorus derivatives, 1a-e, is described. The derivatives were incorporated into a series (18) of analogues of the 5-14 portion of angiotensinogen, in most cases at the scissile Leu-Val bond. The resultant compounds were tested in
J Bird et al.
Journal of medicinal chemistry, 37(1), 158-169 (1994-01-07)
The synthesis of a series of N-phosphonalkyl dipeptides 6 is described. Syntheses were devised that allowed the preparation of single diastereoisomers and the assignment of stereochemistry. The compounds were evaluated in vitro for their ability to inhibit the degradation of
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