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Merck
CN

469157

Sigma-Aldrich

6-羟基-2-萘甲酸

98%

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线性分子式:
HOC10H6CO2H
CAS号:
分子量:
188.18
Beilstein:
2692084
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

mp

240-250 °C (lit.)

SMILES字符串

OC(=O)c1ccc2cc(O)ccc2c1

InChI

1S/C11H8O3/c12-10-4-3-7-5-9(11(13)14)2-1-8(7)6-10/h1-6,12H,(H,13,14)

InChI key

KAUQJMHLAFIZDU-UHFFFAOYSA-N

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一般描述

6-羟基-2-萘甲酸是一种羟基萘甲酸衍生物。据报道,表达CYP199A2的重组大肠杆菌全细胞可催化6-羟基-2-萘甲酸区域选择性氧化成为6,7-二羟基萘甲酸。可与咖啡因形成共晶。

应用

6-羟基-2-萘甲酸可用于合成5-溴-6-羟基-2-萘甲酸 和液晶环氧树脂。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Synthesis and characterization of wholly aromatic polyesters derived from 6-hydroxy-5-phenyl-2-naphthoic acid or 4'-hydroxy-3'-phenylbiphenyl-4-carboxylic acid and 4-hydroxybenzoic acid.
Huh S-M and Jin J.
Macromolecules, 30(10), 3005-3013 (1997)
Dejan-Kresimir Bucar et al.
Molecular pharmaceutics, 4(3), 339-346 (2007-05-11)
A group of caffeine-containing co-crystals of hydroxy-2-naphthoic acids were synthesized and analyzed via single-crystal X-ray diffraction and IR analysis. The imidazole-carboxylic acid synthon was observed in co-crystals involving 1-hydroxy-2-naphthoic and 3-hydroxy-2-naphthoic acid. In the case of 6-hydroxy-2-naphthoic acid, the co-crystal
New cholesteric liquid-crystal epoxy resins derived from 6-hydroxy-2-naphthoic acid.
Espinosa MA, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 39(16), 2847-2858 (2001)
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Kwi-wan Jeong et al.
Chemical & pharmaceutical bulletin, 61(7), 740-746 (2013-07-03)
Folding of newly synthesized protein occurs in endoplasmic reticulum (ER) and is assisted by chaperone molecules. In ER stress conditions, misfolded proteins are enriched in a lumen of ER perturbing its normal function, which triggers cellular self-defense mechanism, the unfolded

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