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Merck
CN

459313

Boc-Cys(Trt)-OH

97%, for peptide synthesis

别名:

N-(叔丁氧羰基)-S-三苯甲基-L-半胱氨酸, Nα-Boc-S-三苯甲基-L-半胱氨酸

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关于此项目

线性分子式:
(C6H5)3CSCH2CH[NHCO2C(CH3)3]CO2H
化学文摘社编号:
21947-98-8
分子量:
463.59
NACRES:
NA.22
PubChem Substance ID:
24869538
UNSPSC Code:
12352209
EC Number:
244-674-6
MDL number:
MFCD00038251
Beilstein/REAXYS Number:
2028965

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产品名称

Boc-Cys(Trt)-OH, 97%

InChI key

JDTOWOURWBDELG-QHCPKHFHSA-N

InChI

1S/C27H29NO4S/c1-26(2,3)32-25(31)28-23(24(29)30)19-33-27(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,28,31)(H,29,30)/t23-/m0/s1

SMILES string

CC(C)(C)OC(=O)N[C@@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)C(O)=O

assay

97%

optical activity

[α]20/D +27.5°, c = 1 in ethanol

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

143-146 °C (lit.)

application(s)

peptide synthesis

Quality Level

200

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相关类别

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM4705
BCCL6185
BCCL3434
BCCJ9757
BCCH6175

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Sunithi Gunasekera et al.
International journal of peptide research and therapeutics, 19(1), 43-54 (2013-03-19)
The development of synthetic methodologies for cyclic peptides is driven by the discovery of cyclic peptide drug scaffolds such as the plant-derived cyclotides, sunflower trypsin inhibitor 1 (SFTI-1) and the development of cyclized conotoxins. Currently, the native chemical ligation reaction
Yang Zhang et al.
ACS applied materials & interfaces, 11(31), 27529-27535 (2019-07-11)
Characterizing over-expressed enzymes or biomarkers in living cells is critical for the molecular understanding of disease pathology and consequently for designing precision medicines. Herein, a "switch-on" probe is designed to selectively detect γ-glutamyl transpeptidase (GGT) in living cells via a
Naohisa Ogo et al.
Bioorganic & medicinal chemistry letters, 17(14), 3921-3924 (2007-05-26)
Inhibition of Eg5 represents a novel approach for the treatment of cancer. Here, we report the synthesis and structure-activity relationship of S-trityl-L-cysteine (STLC) derivatives as Eg5 inhibitors. Some of these derivatives such as 4f demonstrated enhanced inhibitory activity against Eg5

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