质量水平
检测方案
98%
形式
solid
mp
174-177 °C (lit.)
SMILES字符串
O=Cc1c[nH]cn1
InChI
1S/C4H4N2O/c7-2-4-1-5-3-6-4/h1-3H,(H,5,6)
InChI key
ZQEXIXXJFSQPNA-UHFFFAOYSA-N
一般描述
4-咪唑吡啶甲醛在硼氢化钠存在下与胺发生还原胺化反应，生成仲胺。
应用
4-咪唑甲醛可用于以下研究：
- 新型供体-Π-受体（D-Π-A）型染料的合成。
- 制备尿刊、正十二烷基和正十二烷基酯的尿刊（4-咪唑丙烯酸）。
- 比色化学传感器的制备。
- 手性镍（II）络合物 [Ni(II)H3L]（ClO4)2 的合成，具有非手性配体 H3L（三{2-（4-咪唑基）甲基亚氨基乙基}胺）。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Peter B Madrid et al.
Journal of combinatorial chemistry, 6(3), 437-442 (2004-05-11)
Due to growing problems with drug resistance, there is an outstanding need for new, cost-effective drugs for the treatment of malaria. The 4-aminoquinolines have provided a number of useful antimalarials, and Plasmodium falciparum, the causative organism for the most deadly
Organic Process Research & Development, 11, 206-206 (2007)
Chromene and Imidazole Based D-p-A Chemosensor Preparation and Its Anion Responsive Effects.
Son YA, et al.
Mol. Cryst. Liq. Cryst., 599(1), 16-22 (2014)
Spontaneous Resolution Induced by a Chiral Ni (II) Complex with an Achiral Tripodal Ligand#.
Sarkar S, et al.
Bull. Korean Chem. Soc., 36(3), 838-842 (2015)
K Honda et al.
Journal of pharmaceutical sciences, 70(1), 98-99 (1981-01-01)
Ethyl, n-dodecyl, and n-hexadecyl esters of urocanic acid (4-imidazoleacrylic acid) were prepared from 4-imidazolecarboxaldehyde in satisfactory yields via the Wittig reaction.
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