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关于此项目
经验公式(希尔记法):
C10H19NO3
化学文摘社编号:
分子量:
201.26
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3542667
产品名称
N-Boc-L-脯氨醇, 98%
InChI
1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(11)7-12/h8,12H,4-7H2,1-3H3/t8-/m0/s1
SMILES string
CC(C)(C)OC(=O)N1CCC[C@H]1CO
InChI key
BFFLLBPMZCIGRM-QMMMGPOBSA-N
assay
98%
form
solid
optical activity
[α]21/D −48°, c = 1.3 in chloroform
reaction suitability
reaction type: Boc solid-phase peptide synthesis
mp
62-64 °C (lit.)
application(s)
peptide synthesis
Quality Level
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Application
用于合成抗凝剂。
用于新型烟碱型乙酰胆碱受体配体(具有强化识别性)的结构单元。用于合成手性 β-氨基硫醚和 β-氨基硫醇。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
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N H Lin et al.
Journal of medicinal chemistry, 40(3), 385-390 (1997-01-31)
2-Methyl-3-(2(S)-pyrrolidinylmethoxy)pyridine, ABT-089 (S-4), a member of the 3-pyridyl ether class of nicotinic acetylcholine receptor (nAChR) ligands, shows positive effects in rodent and primate models of cognitive enhancement and a rodent model of anxiolytic activity and possesses a reduced propensity to
Cran, G.A. et al.
Tetrahedron Asymmetry, 6, 1553-1553 (1995)
Elliott, R.L. et al.
Bioorganic & Medicinal Chemistry Letters, 6, 2283-2283 (1996)
M A Abreo et al.
Journal of medicinal chemistry, 39(4), 817-825 (1996-02-16)
Recent evidence indicating the therapeutic potential of cholinergic channel modulators for the treatment of central nervous system (CNS) disorders as well as the diversity of brain neuronal nicotine acetylcholine receptors (nAChRs) have suggested an opportunity to develop subtype-selective nAChR ligands
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