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Merck
CN

445088

Sigma-Aldrich

丙二酸单乙酯

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别名:
3-乙氧基-3-氧代丙酸, 丙二酸乙酯, 丙二酸氢乙酯, 单乙基氢丙二酸酯, (乙氧基羰基)乙酸
线性分子式:
HO2CCH2CO2C2H5
CAS号:
分子量:
132.11
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

形式

liquid

杂质

<10% ethyl malonate, potassium salt

折射率

n20/D 1.435 (lit.)

bp

106.5 °C/3 mmHg (lit.)

密度

1.119 g/mL at 25 °C (lit.)

SMILES字符串

CCOC(=O)CC(O)=O

InChI

1S/C5H8O4/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3,(H,6,7)

InChI key

HGINADPHJQTSKN-UHFFFAOYSA-N

应用

反应物用于:
  • 通过Dieckmann闭环方法制备特特拉姆酸
  • 有机催化脱羧Doebner-Knoevenagel反应
  • 与氨基修饰的寡核苷酸缀合
  • 酰化反应(酰化剂)
  • 用于潜在的朊病毒病治疗的吲哚乙醛酰胺
  • 与醛的Knoevenagel缩合反应

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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商品

Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

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