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440744

Sigma-Aldrich

聚已酸内酯

greener alternative

average Mn 80,000

别名:

2-氧杂环庚烷酮均聚物, 6-己内酯聚合物

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5 G
¥829.76
250 G
¥2,203.86
500 G
¥3,796.61

¥829.76

国内现货，预计发货时间2025年4月07日详情

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5 G
¥829.76
250 G
¥2,203.86
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¥3,796.61

About This Item

线性分子式:
(C6H10O2)n
UNSPSC代码:
12162002
NACRES:
NA.23

¥829.76

国内现货，预计发货时间2025年4月07日详情

获取大包装报价

表单

pellets (~3 mm)

分子量

average Mn 80,000

环保替代产品特性

Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

杂质

<0.5% water

mp

60 °C (lit.)

密度

1.145 g/mL at 25 °C

Mw/Mn

<2

应用

3D bioprinting
advanced drug delivery

环保替代产品分类

Enabling

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此商品
704105900820900822
聚已酸内酯 average Mn 80,000

440744

聚已酸内酯

聚已酸内酯 average Mn 45,000

704105

聚已酸内酯

聚己内酯 viscosity 1.7&#160;dL/g&#160;

900820

聚己内酯

聚己内酯 viscosity 1.2&#160;dL/g&#160;

900822

聚己内酯

density

1.145 g/mL at 25 °C

density

-

density

-

density

-

mp

60 °C (lit.)

mp

56-64 °C, 60 °C (lit.)

mp

-

mp

-

mol wt

average Mn 80,000

mol wt

Mn 40,000-50,000, Mw 48,000-90,000, average Mn 45,000

mol wt

-

mol wt

-

impurities

<0.5% water

impurities

-

impurities

≤0.5 Residual monomer (GC), ≤0.5% Residual Water content (colormetric titration), ≤100 ppm Tin (AAS)

impurities

≤0.5% Residual monomer (GC), ≤0.5% Residual water content (colormetric titration), ≤100 ppm Tin (AAS)

Mw/Mn

<2

Mw/Mn

-

Mw/Mn

-

Mw/Mn

-

一般描述

聚己内酯(PCL)是一种半晶态疏水性可生物降解聚酯，具有成本低、韧性好、生物相容性好等优点，在医药领域有着广泛的应用。PCL具有一些独特的性质，如:
  • 在生理条件下，它的降解速度比其他生物可降解聚酯慢，这一特性可以在一段时间内用于靶组织药物的可控释放。
  • 由于其疏水性，其表面润湿性较差，与生物液体的相互作用较差，导致较差的细胞黏附和增殖能力，因此与其他合成/天然聚合物混合使用。[1]
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This is an enabling product that belongs to a family of high-performance bio-based polymers that are essential for developing efficient, low-cost, and environmentally friendly renewable energy solutions. Click here for more information.

应用

  • 负载抗生素的PCL可用于治疗呼吸道感染，如肺结核。
  • 已有研究关于人骨髓间充质细胞(hBMSCs)对不同比例的壳聚糖/聚己内酯(PCL)共混物的表型反应。[1]
  • PCL/生物医用陶瓷材料已被研究用于可能的骨组织再生。
  • PCL/分级胰岛素/beta-5甘油磷酸酯浓度通过脂肪来源的基质细胞分化对骨软骨组织形成的作用。[2]
  • 其它通用用途包括:压出助剂、模具润滑剂、脱模剂、颜料和填料分散助剂以及聚氨酯和嵌段聚酯中的聚酯段。

特点和优势

可生物降解聚合物
无毒、土壤中可生物降解、混合性优异、与许多聚合物具有机械相容性以及对许多基质具有良好粘性。

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000407025
    0000366293
    0000345170
    0000342370
    0000306693

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    Hung-Jen Shao et al.
    Journal of biomedical materials research. Part A, 100(12), 3344-3352 (2012-06-27)
    The phenotypic responses of human bone marrow mesenchymal cells (hBMSCs) on different ratio of chitosan/polycaprolactone (PCL) blends were investigated in this study. The results showed that hBMSCs existed different morphology on chitosan/PCL blends due to the different adhesion characteristic of
    Cevat Erisken et al.
    Tissue engineering. Part A, 17(9-10), 1239-1252 (2010-12-30)
    The ability to fabricate tissue engineering scaffolds containing systematic gradients in the distributions of stimulators provides additional means for the mimicking of the important gradients observed in native tissues. Here the concentration distributions of two bioactive agents were varied concomitantly
    Muhammad Shafiq et al.
    Arteriosclerosis, thrombosis, and vascular biology, 38(7), e117-e134 (2018-06-02)
    The objective of this study was to develop small-diameter vascular grafts capable of eluting SDF (stromal cell-derived factor)-1α-derived peptide and SP (substance P) for in situ vascular regeneration. Polycaprolactone (PCL)/collagen grafts containing SP or SDF-1α-derived peptide were fabricated by electrospinning.
    T Limongi et al.
    Molecular neurobiology, 55(12), 8788-8798 (2018-03-31)
    Biopolymers are increasingly employed for neuroscience applications as scaffolds to drive and promote neural regrowth, thanks to their ability to mediate the upload and subsequent release of active molecules and drugs. Synthetic degradable polymers are characterized by different responses ranging
    Wei Ching Low et al.
    Biomaterials, 34(14), 3581-3590 (2013-02-19)
    At present, the recovery prospect for patients with chronic neurodegenerative diseases or acute trauma in the central nervous system is sub-optimal. The controlled differentiation of neural stem/progenitor cells (NPCs) to functional neurons is a possible treatment strategy. In contrast to
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