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Merck
CN

440736

Sigma-Aldrich

4-硫尿嘧啶

97%

别名:

2-羟基-4-巯基嘧啶

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About This Item

经验公式(希尔记法):
C4H4N2OS
CAS号:
分子量:
128.15
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

97%

表单

powder

mp

295 °C (dec.) (lit.)

溶解性

1 M NaOH: soluble 50 mg/mL

SMILES字符串

Oc1nccc(S)n1

InChI

1S/C4H4N2OS/c7-4-5-2-1-3(8)6-4/h1-2H,(H2,5,6,7,8)

InChI key

OVONXEQGWXGFJD-UHFFFAOYSA-N

应用

4-硫尿嘧啶是在RNA提取过程中,用于胚胎的Schneider培养基中的合适试剂。 它可以用作 Northwestern印迹技术中的试剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Linda Warfield et al.
Molecular cell, 68(1), 118-129 (2017-09-19)
Previous studies suggested that expression of most yeast mRNAs is dominated by either transcription factor TFIID or SAGA. We re-examined the role of TFIID by rapid depletion of S. cerevisiae TFIID subunits and measurement of changes in nascent transcription. We find that
Margaret A Nakamoto et al.
RNA (New York, N.Y.), 23(12), 1834-1849 (2017-08-31)
RNA contains over 100 modified nucleotides that are created post-transcriptionally, among which pseudouridine (Ψ) is one of the most abundant. Although it was one of the first modifications discovered, the biological role of this modification is still not fully understood.
Qing S Wang et al.
RNA (New York, N.Y.), 11(4), 404-411 (2005-02-11)
Isolating the core functional elements of an RNA is normally performed during the characterization of a new RNA in order to simplify further biochemical analysis. The removal of extraneous sequence is challenging and can lead to biases that result from
Structure and tautomerism of the neutral and monoanionic forms of 4-thiouracil derivatives.
A Psoda et al.
Journal of the American Chemical Society, 96(22), 6832-6839 (1974-10-30)
Jeanine S Morey et al.
PloS one, 8(6), e66347-e66347 (2013-06-19)
Dinoflagellates possess many physiological processes that appear to be under post-transcriptional control. However, the extent to which their genes are regulated post-transcriptionally remains unresolved. To gain insight into the roles of differential mRNA stability and de novo transcription in dinoflagellates

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