所有图片(2)
About This Item
线性分子式:
C6H5SO3CF3
CAS号:
分子量:
226.17
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
检测方案
98%
形式
liquid
折射率
n20/D 1.435 (lit.)
bp
99-100 °C/60 mmHg (lit.)
密度
1.396 g/mL at 25 °C (lit.)
SMILES字符串
FC(F)(F)S(=O)(=O)Oc1ccccc1
InChI
1S/C7H5F3O3S/c8-7(9,10)14(11,12)13-6-4-2-1-3-5-6/h1-5H
InChI key
GRJHONXDTNBDTC-UHFFFAOYSA-N
一般描述
苯基三氟甲烷磺酸酯（三氟甲磺酸苯酯）是一种芳基氟代磺酸酯。可通过苯酚与氟磺酸酐反应合成。
应用
三氟甲磺酸苯酯可用于以下研究：
- 作为芳基化剂，用于Pd(dba)2和difluorphos催化的酮的不对称α-芳基化反应。
- 作为咔唑的一锅法合成的反应物，用于钯催化的苯胺与芳基三氟甲磺酸酯的N-芳基化反应，然后进行氧化偶联。
- 用于钯催化的苯甲酰苯胺与三氟甲磺酸苯酯的二芳基化反应，合成N-(2,6-二芳基苯甲酰基)苯胺。
- 作为芳基化剂，用于2,3-二氢呋喃的芳基化反应，以合成(R)-2-苯基-2,3-二氢呋喃。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Skin Corr. 1B
WGK
WGK 3
闪点(°F)
159.8 °F
闪点(°C)
71 °C
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling.
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Tetrahedron Letters, 41(15), 2655-2658 (2000)
Xuebin Liao et al.
Journal of the American Chemical Society, 130(1), 195-200 (2007-12-14)
The asymmetric alpha-arylation of ketones with aryl triflates is described, and the use of this electrophile with nickel and palladium catalysts containing a segphos derivative increases substantially the scope of highly enantioselective arylations of ketone enolates. The combination of aryl
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