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质量水平
方案
97%
mp
113-115 °C (lit.)
官能团
amine
fluoro
oxime
SMILES字符串
N\C(=N/O)c1ccc(OC(F)(F)F)cc1
InChI
1S/C8H7F3N2O2/c9-8(10,11)15-6-3-1-5(2-4-6)7(12)13-14/h1-4,14H,(H2,12,13)
InChI key
COHKFOZYLCDVRK-UHFFFAOYSA-N
一般描述
4-(Trifluoromethoxy)benzamidoxime (4-TFMBAO) is a benzamidoxime (BAO) derivative containing amidoxime functional group. Its density and freezing point have been determined.
应用
4-(Trifluoromethoxy)benzamidoxime (4-TFMBAO) is suitable reactant in the fluorescence (FL) deriving reaction, one of the widely-used methodology specifically used to quantify uracil. It may be used as a reactant in the synthesis of oxadiazoles. It may also be used a fluorogenic agent in the quantification of orotic acid by spectrofluorometric method in human biological specimens.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Sensitive and Selective Determination of Orotic Acid in Biological Specimens Using a Novel Fluorogenic Reaction.
Journal of Fluorescence, 25(4), 1005-1011 (2015)
Bioorganic & medicinal chemistry letters, 21(10), 2820-2822 (2011-04-22)
Seeking compounds preferentially potent and selective for MMP-13, we reported in the preceding Letter on a series of hydroxamic acids with a flexible benzamide tail groups.(1a) Here, we replace the amide moiety with non-hydrolyzable heterocycles in an effort to improve
The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals, 185-185 (2015)
Cell chemical biology, 27(2), 197-205 (2019-11-18)
Biosynthesis of the pyrimidine nucleotide uridine monophosphate (UMP) is essential for cell proliferation and is achieved by the activity of convergent de novo and salvage metabolic pathways. Here we report the development and application of a cell-based metabolic modifier screening
Analytica chimica acta, 674(2), 234-238 (2010-08-04)
Facile and specific methods to quantify a nucleobase in biological samples are of great importance for diagnosing disorders in nucleic acid metabolism. In the present study, a novel fluorogenic reaction specific for uracil has been developed. The reaction was carried
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