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Merck
CN

420247

(+)-冰片

97%

别名:

内型-(1R)-1,7,7-三甲基二环[2.2.1]庚-2-醇

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关于此项目

经验公式(希尔记法):
C10H18O
化学文摘社编号:
分子量:
154.25
UNSPSC Code:
12352212
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-352-6
Beilstein/REAXYS Number:
2038056
MDL number:
Assay:
97%
Form:
solid
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InChI key

DTGKSKDOIYIVQL-WEDXCCLWSA-N

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1

SMILES string

[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C

assay

97%

form

solid

optical activity

[α]20/D +36°, c = 5 in ethanol

Quality Level

Gene Information

human ... UGT1A4(54657)

mp

206-209 °C (lit.)

functional group

hydroxyl

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General description

(+)-冰片是一种双环单萜,于药用植物精油中发现,常用于中药,起到镇痛和麻醉作用。

Application

(+)-冰片在人神经母细胞瘤细胞(SH-SY5Y)中已被用于研究其对抗凋亡、抗氧化和神经保护作用。

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。

pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Sol. 2

存储类别

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

149.0 °F - closed cup

flash_point_c

65 °C - closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
Hur J, et al.
Pharmaceutical Analysis, 51(1), 30-35 (2013)
(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jianyu Su et al.
Journal of food science, 77(6), C658-C664 (2012-05-16)
The aims of this study were to optimize the preparation conditions of natural borneol/β-cyclodextrin (NB/β-CD) inclusion complex by ultrasound method, and to investigate its improvement of stability and solubility. The complex was characterized by different various spectroscopic techniques including Fourier
Wan Ren-Zhong et al.
Journal of Asian natural products research, 14(6), 538-544 (2012-05-17)
The main purpose of this study was to illustrate the effect of borneol on pharmacokinetics of salvianolic acid B (SalB) in rats after oral administration of SalB with different doses of borneol. The concentrations of SalB in rat plasma were
Xiao Song et al.
Die Pharmazie, 67(10), 848-851 (2012-11-10)
The aim of this work was to study the in situ and in vivo nasal absorption of borneol. A novel single pass in situ nasal perfusion technique was applied to examine the rate and extent of nasal absorption of borneol

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