420247
(+)-冰片
97%
别名:
内型-(1R)-1,7,7-三甲基二环[2.2.1]庚-2-醇
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关于此项目
经验公式（希尔记法）:
C10H18O
化学文摘社编号:
分子量:
154.25
Beilstein:
2038056
EC 号:
MDL编号:
UNSPSC代码:
12352212
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
97%
表单
solid
旋光性
[α]20/D +36°, c = 5 in ethanol
mp
206-209 °C (lit.)
官能团
hydroxyl
SMILES字符串
[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C
InChI
1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1
InChI key
DTGKSKDOIYIVQL-WEDXCCLWSA-N
基因信息
human ... UGT1A4(54657)
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一般描述
(+)-冰片是一种双环单萜，于药用植物精油中发现，常用于中药，起到镇痛和麻醉作用。
应用
(+)-冰片在人神经母细胞瘤细胞（SH-SY5Y）中已被用于研究其对抗凋亡、抗氧化和神经保护作用。
包装
无底玻璃瓶。内含物在插入的融合锥体内。
警示用语：
Warning
危险声明
危险分类
Flam. Sol. 2
储存分类代码
4.1B - Flammable solid hazardous materials
WGK
WGK 3
闪点(°F)
149.0 °F - closed cup
闪点(°C)
65 °C - closed cup
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
Hur J, et al.
Pharmaceutical Analysis, 51(1), 30-35 (2013)
(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jing-yi Zhao et al.
Journal of Zhejiang University. Science. B, 13(12), 990-996 (2012-12-12)
Borneol, a monoterpenoid alcohol, is used widely, particularly in combined formulas for preventing and curing cardiovascular and cerebrovascular diseases in traditional Chinese medicine. In order to understand the blood and brain pharmacokinetics after intravenous, intranasal, or oral administration and to
Xiao Song et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(18), 2489-2492 (2012-01-20)
To investigate the absorption characteristic of borneol. Using single pass perfusion model, the active ingredient of borneol were detected by GC. The drug concentration, perfusion rate and pH value on the absorption of borneol were studied. Perfusion rate on the
Na Zhang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(22), 3180-3183 (2012-03-02)
To research the content changes of excitatory neurotransmitter and inhibitory neurotransmitter in corpus striatum of rats after single-used borneol and combining it with diazepam in hope of comprehending the activity of borneol on central nervous system and to observe whether
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