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Merck
CN

420174

Sigma-Aldrich

顺-3-羟基-DL-脯氨酸

95%

别名:

(±)-顺式-3-羟基吡咯烷-2-羧酸

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About This Item

经验公式(希尔记法):
C5H9NO3
CAS号:
分子量:
131.13
Beilstein:
4130229
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

方案

95%

反应适用性

reaction type: solution phase peptide synthesis

mp

232 °C (dec.) (lit.)

应用

peptide synthesis

SMILES字符串

O[C@@H]1CCN[C@@H]1C(O)=O

InChI

1S/C5H9NO3/c7-3-1-2-6-4(3)5(8)9/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1

InChI key

BJBUEDPLEOHJGE-DMTCNVIQSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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David M Hudson et al.
Biochemistry, 51(12), 2417-2424 (2012-03-03)
Proline residues in collagens are extensively hydroxylated post-translationally. A rare form of this modification, (3S,2S)-l-hydroxyproline (3Hyp), remains without a clear function. Disruption of the enzyme complex responsible for prolyl 3-hydroxylation results in severe forms of recessive osteogenesis imperfecta (OI). These
Stephen M Krane
Amino acids, 35(4), 703-710 (2008-04-24)
Collagens are among proteins that undergo several post-translational modifications, such as prolyl hydroxylation, that occur during elongation of the nascent chains in the endoplasmic reticulum. The major structural collagens, types I, II and III, have large, uninterrupted triple helices, comprising
A J Bos et al.
Nihon eiseigaku zasshi. Japanese journal of hygiene, 49(4), 797-806 (1994-10-01)
to observe the influence of aging on urinary secretion of 3-hydroxyproline (3-Hyp) in normal subjects and in cancer patients and study the effects of aging on the accuracy of urinary 3-Hyp as a general-purpose cancer screening test. We reanalyzed, from
A new rapid method for quantitating radioactive proline, 4-hydroxyproline, and 3-hydroxyproline.
S C Tseng et al.
Analytical biochemistry, 102(2), 291-299 (1980-03-01)
Determination of 3- and 4-hydroxyproline.
R A Berg
Methods in enzymology, 82 Pt A, 372-398 (1982-01-01)

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