推荐产品
产品名称
N-羟基-7-偶氮苯并三氮唑 溶液, ~0.6 M in DMF
表单
liquid
质量水平
反应适用性
reaction type: Addition Reactions
浓度
~0.6 M in DMF
杂质
<1.0% water
折射率
n20/D 1.441
密度
0.978 g/mL at 20 °C
应用
peptide synthesis
SMILES字符串
On1nnc2cccnc12
InChI
1S/C5H4N4O/c10-9-5-4(7-8-9)2-1-3-6-5/h1-3,10H
InChI key
FPIRBHDGWMWJEP-UHFFFAOYSA-N
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一般描述
1-羟基-7-氮杂苯并三唑溶液，又称3H-[1,2,3]-三唑并[4,5-b]吡啶-3-醇，是一种苯并三唑类添加剂，常用作氨基酸和肽的偶联试剂。它还被用于最小化对映异构体生成。
应用
1-羟基-7-氮杂苯并三唑溶液被用作手性肽核酸的固相合成试剂。
其他说明
偶联添加剂，用于肽合成中的高效无外消旋偶联； 片段偶联。
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
136.4 °F - closed cup
闪点(°C)
58 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Oxyma-B, an excellent racemization suppressor for peptide synthesis
Yahya JE,et al.
Organic & Biomolecular Chemistry, 12, 8379-8385 (2014)
Hsuan-Ni Lin et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 34(11), 1883-1893 (2016-02-27)
Fracture healing is regulated by a variety of inflammatory mediators and growth factors which act over time to regenerate the injured tissue. This study used a mouse femur fracture model to quantify the temporal expression pattern of lipid mediators, cytokines
Synthesis of chiral peptide nucleic acids using Fmoc chemistry
Yun W and Jie-Cheng X
Tetrahedron, 57, 8107-8113 (2001)
L.A. Carpino, A. El-Faham
Tetrahedron, 55, 6813-6813 (1999)
Simone Di Micco et al.
Frontiers in chemistry, 8, 628609-628609 (2021-02-02)
The most severe outcome of COVID-19 infection is the development of interstitial pneumonia causing acute lung injury (ALI) and/or acute respiratory distress syndrome (ARDS), both responsible for the infected patients' mortality. ALI and ARDS are characterized by a leakage of
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