419648
2,5-二叔丁基-1,4-苯醌
99%
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线性分子式:
[(CH3)3C]2C6H2(=O)2
化学文摘社编号:
分子量:
220.31
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
219-552-0
MDL number:
Assay:
99%
InChI key
ZZYASVWWDLJXIM-UHFFFAOYSA-N
InChI
1S/C14H20O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8H,1-6H3
SMILES string
CC(C)(C)C1=CC(=O)C(=CC1=O)C(C)(C)C
assay
99%
mp
152-154 °C (lit.)
functional group
ketone
Quality Level
General description
2,5-二叔丁基-1,4-苯醌（DTBBQ）是一种2,5-二取代醌。它是一种从海洋链霉菌Streptomyces sp. VITVSK1中分离出来的抗菌化合物。 已有研究使用高压EPR技术，评估了2,5-二叔丁基-1,4-苯醌离子对中Na+和K+的分子内和分子间迁移速率的压力依赖性。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Y K Ju et al.
The Journal of physiology, 525 Pt 3, 695-705 (2000-06-16)
The mechanisms of sarcoplasmic reticulum (SR) Ca2+ release in pacemaker cells from the sinus venosus of the cane toad (Bufo marinus) were studied. Single, isolated cells were voltage clamped using a nystatin-perforated patch. Ionic currents and intracellular Ca2+ concentration ([Ca2+]i)
Catalytic aerobic deamination of activated primary amines by a model for the quinone cofactor of mammalian copper amine oxidases.
L M Sayre et al.
Methods in enzymology, 258, 53-69 (1995-01-01)
H Westerblad et al.
The Journal of physiology, 474(2), 291-301 (1994-01-15)
1. Intracellular calcium concentration ([Ca2+]i) and force were measured from isolated single mouse skeletal muscle fibres at rest and during tetani. The actions of 2,5-di(tert-butyl)-1,4-benzohydroquinone (TBQ), an inhibitor of the sarcoplasmic reticulum (SR) Ca2+ pump, were examined at a range
M T Clunes et al.
Cell calcium, 20(4), 339-346 (1996-10-01)
The human lung small cell adenocarcinoma cell line, A549, demonstrates a concentration-dependent rise in [Ca2+]i in response to extracellular nucleotides. The cells show Ca2+ mobilization on addition of various nucleotides, with an order of agonist potency: UTP > or =
Pressure effects on cation migration in 2, 5-di-tert-butyl-1, 4-benzoquinone radical anion.
Kasahara M, et al.
International Journal of Chemical Kinetics, 33(7), 397-401 (2001)
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