419648
2,5-二叔丁基-1,4-苯醌
99%
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线性分子式:
[(CH3)3C]2C6H2(=O)2
化学文摘社编号:
分子量:
220.31
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
219-552-0
MDL number:
Assay:
99%
InChI key
ZZYASVWWDLJXIM-UHFFFAOYSA-N
InChI
1S/C14H20O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8H,1-6H3
SMILES string
CC(C)(C)C1=CC(=O)C(=CC1=O)C(C)(C)C
assay
99%
mp
152-154 °C (lit.)
functional group
ketone
Quality Level
General description
2,5-二叔丁基-1,4-苯醌（DTBBQ）是一种2,5-二取代醌。它是一种从海洋链霉菌Streptomyces sp. VITVSK1中分离出来的抗菌化合物。 已有研究使用高压EPR技术，评估了2,5-二叔丁基-1,4-苯醌离子对中Na+和K+的分子内和分子间迁移速率的压力依赖性。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
P Adams et al.
The Biochemical journal, 335 ( Pt 1), 131-138 (1998-09-22)
Mutational analysis of trans-membrane helices M3, M4, M5 and M7 of the Ca2+-ATPase revealed a novel phenotypic variant, M4 [Y295A (the one-letter symbols are used for amino acid residues throughout)], displaying an increased affinity for Pi and decreased affinity for
A Lückhoff et al.
Biophysical journal, 67(1), 177-182 (1994-07-01)
Depletion of intracellular calcium stores induces transmembrane Ca2+ influx. We studied Ca(2+)- and Ba(2+)-permeable ion channels in A431 cells after store depletion by dialysis of the cytosol with 10 mM BAPTA solution. Cell-attached patches of cells held at low (0.5
Catalytic aerobic deamination of activated primary amines by a model for the quinone cofactor of mammalian copper amine oxidases.
L M Sayre et al.
Methods in enzymology, 258, 53-69 (1995-01-01)
R J Dolor et al.
The American journal of physiology, 262(1 Pt 1), C171-C181 (1992-01-01)
We have investigated the role of the intracellular Ca2+ pool in regulating Ca2+ entry into vascular endothelial cells. The intracellular Ca2+ pool was mobilized using either thapsigargin (TG) or 2',5'-di(tert-butyl)-1,4-benzohydroquinone (BHQ), inhibitors of the endoplasmic reticulum Ca(2+)-adenosinetriphosphatase (ATPase). Mobilization of
Y K Ju et al.
The Journal of physiology, 525 Pt 3, 695-705 (2000-06-16)
The mechanisms of sarcoplasmic reticulum (SR) Ca2+ release in pacemaker cells from the sinus venosus of the cane toad (Bufo marinus) were studied. Single, isolated cells were voltage clamped using a nystatin-perforated patch. Ionic currents and intracellular Ca2+ concentration ([Ca2+]i)
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