412260
苯氧肟酸
99%
别名:
苯甲羟肟酸
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关于此项目
线性分子式:
C6H5CONHOH
化学文摘社编号:
分子量:
137.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-797-6
Beilstein/REAXYS Number:
1907585
MDL number:
产品名称
苯氧肟酸, 99%
InChI key
VDEUYMSGMPQMIK-UHFFFAOYSA-N
InChI
1S/C7H7NO2/c9-7(8-10)6-4-2-1-3-5-6/h1-5,10H,(H,8,9)
SMILES string
ONC(=O)c1ccccc1
assay
99%
mp
126-130 °C (lit.)
solubility
1 M NaOH: soluble 50 mg/mL, clear, colorless
functional group
amine
phenyl
storage temp.
2-8°C
Quality Level
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Application
苯异羟肟酸可用于Pd催化的苯并异恶唑酮合成。
General description
苯异羟肟酸（BHA）与BiPh3或Bi(O(t)Bu)3反应，得到具有抗幽门螺杆菌活性的新型单阴离子和二阴离子异羟肟酸复合物。 已研究了重组辣根过氧化物酶-BHA复合物的三维结构。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Henrik R Hallingbäck et al.
Biochemistry, 45(9), 2940-2950 (2006-03-01)
The oxidation of melatonin by the mammalian myeloperoxidase (MPO) provides protection against the damaging effects of reactive oxygen species. Indole derivatives, such as melatonin and serotonin, are also substrates of the plant horseradish peroxidase (HRP), but this enzyme exhibits remarkable
Nicolas Guimond et al.
Journal of the American Chemical Society, 132(20), 6908-6909 (2010-05-04)
An external-oxidant-free process to access the isoquinolone motif via cross-coupling/cyclization of benzhydroxamic acid with alkynes is described. The reaction features a regioselective cleavage of a C-H bond on the benzhydroxamic acid coupling partner as well as a regioselective alkyne insertion.
Fernando Ruy et al.
Journal of bioenergetics and biomembranes, 38(2), 129-135 (2006-10-21)
Candida parapsilosis mitochondria contain three respiratory chains: the classical respiratory chain (CRC), a secondary parallel chain (PAR) and an "alternative" oxidative pathway (AOX). We report here the existence of similar pathways in C. albicans. To observe the capacity of each
Florian Thaler et al.
Journal of medicinal chemistry, 53(2), 822-839 (2009-12-19)
The histone deacetylases (HDACs) are able to regulate gene expression, and histone deacetylase inhibitors (HDACi) emerged as a new class of agents in the treatment of cancer as well as other human disorders such as neurodegenerative diseases. In the present
Swetlana Gez et al.
Inorganic chemistry, 44(8), 2934-2943 (2005-04-12)
A new family of relatively stable Cr(V) complexes, [Cr(V)O(L)(2)](-) (LH(2) = RC(O)NHOH, R = Me, Ph, 2-HO-Ph, or HONHC(O)(CH(2))(6)), has been obtained by the reactions of hydroxamic acids with Cr(VI) in polar aprotic solvents. Similar reactions in aqueous solutions led
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