assay
98%
form
solid
InChI key
GPZYYYGYCRFPBU-UHFFFAOYSA-N
InChI
1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H
SMILES string
Oc1ccc2OC(=CC(=O)c2c1)c3ccccc3
mp
234-236 °C (lit.)
functional group
ketone, phenyl
Quality Level
Gene Information
rat ... Ar(24208), Gabra2(29706)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Structure of 6-hydroxyflavone.
Seetharaman J and Rajan SS.
Acta Crystallographica Section C, Structural Chemistry, 48(9), 1714-1715 (1992)
Xing Wang et al.
PloS one, 10(3), e0116409-e0116409 (2015-03-20)
Inflammatory responses by kidney mesangial cells play a critical role in the glomerulonephritis. The anti-inflammatory potential of nineteen mono-, di- and polyhydroxylated flavones including fisetin, quercetin, morin, tricetin, gossypetin, apigenin and myricetin were investigated on rat mesangial cells with lipopolysaccharide
Zia Ud Din et al.
Histology and histopathology, 35(10), 1197-1209 (2020-09-11)
In this study, the flavonoid, 6-hydroxyflavone was investigated for its renal protective activity in the cisplatin rat model of nephrotoxicity. Male Sprague-Dawley rats weighing 200-250 g were included in the study. 6-Hydroxyflavone was daily administered at 25 and 50 mg/kg
Sourav Das et al.
Journal of biomolecular structure & dynamics, 37(15), 4019-4034 (2018-10-14)
The interaction of 6-hydroxyflavone (6HF) with hen egg white lysozyme (HEWL) has been executed using multi-spectroscopic and computational methods. Steady state fluorescence studies indicated that static quenching mechanism is involved in the binding of 6HF with HEWL, which was further
Chien-Hung Lai et al.
Evidence-based complementary and alternative medicine : eCAM, 2014, 924560-924560 (2014-05-06)
Osteoblast differentiation plays an essential role in bone integrity. Isoflavones and some flavonoids are reported to have osteogenic activity and potentially possess the ability to treat osteoporosis. However, limited information concerning the osteogenic characteristics of hydroxyflavones is available. This study
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