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About This Item
经验公式（希尔记法）:
C9H13N3
CAS号:
分子量:
163.22
Beilstein:
140423
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
检测方案
≥99%
形式
liquid
折射率
n20/D 1.595 (lit.)
bp
120-122 °C/2 mmHg (lit.)
密度
1.072 g/mL at 25 °C (lit.)
SMILES字符串
C1CN(CCN1)c2ccccn2
InChI
1S/C9H13N3/c1-2-4-11-9(3-1)12-7-5-10-6-8-12/h1-4,10H,5-8H2
InChI key
GZRKXKUVVPSREJ-UHFFFAOYSA-N
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一般描述
1-（2-吡啶基）哌嗪是一种哌嗪衍生物。
应用
1-（2-吡啶基）哌嗪可作为反相 HPLC 测定空气中脂肪族和芳香族异氰酸酯的试剂。 可作为空气中二异氰酸酯荧光测定的试剂。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Determination of atmospheric isocyanate concentrations by high-performance thin-layer chromatography using 1-(2-pyridyl) piperazine reagent.
Ellwood PA, et al.
Analyst, 106(1258), 85-93 (1981)
Absorption and fluorescence of 1-(2-pyridyl)-piperazine and four diisocyanate derivatives in solution.
Salthammer T, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 107(1), 159-164 (1997)
Harvey Wong et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(8), 1387-1392 (2007-05-15)
The pharmacokinetics and in vivo potency of 6-hydroxybuspirone (6-OH-buspirone), a major metabolite of buspirone, were investigated. The plasma clearance (47.3 +/- 3.5 ml/min/kg), volume of distribution (2.6 +/- 0.3 l/kg), and half-life (1.2 +/- 0.2 h) of 6-OH-buspirone in rats
P Giral et al.
European journal of pharmacology, 134(1), 113-116 (1987-01-28)
We investigated in mice the effects of one of the principal metabolites of buspirone and gepirone, 1-(2-pyridinyl)-piperazine (1-PmP), on hypothermia and reduced locomotion induced by clonidine (0.25 and 0.06 mg/kg, respectively), tests related to brain alpha-adrenergic function. Both effects were
Determination of trace atmospheric isocyanate concentrations by reversed-phase high-performance liquid chromatography using 1-(2-pyridyl) piperazine reagent.
Goldberg PA, et al.
Journal of Chromatography A, 212(1), 93-104 (1981)
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