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检测方案
98%
mp
47-54 °C (lit.)
SMILES字符串
[O-][N+](=O)c1cc(ccc1Cl)C(Cl)=O
InChI
1S/C7H3Cl2NO3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H
InChI key
IWLGXPWQZDOMSB-UHFFFAOYSA-N
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一般描述
4-Chloro-3-nitrobenzoyl chloride is an acid halide.
应用
4-Chloro-3-nitrobenzoyl chloride may be employed as acylation reagent for the Friedel-Crafts acylation of activated benzenes such as anisole, veratrole and 1,4-dimethoxybenzene. It may be employed for the synthesis of 4-chloro-4-methoxy-3-nitrobenzophenone. It may be employed as acylation reagent for the acylation reaction of the deactivated amines (2- aminopyrimidine, aminopyrazine).
警示用语：
Danger
危险声明
危险分类
Skin Corr. 1B
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Insights into the N,N-diacylation reaction of 2-aminopyrimidines and deactivated anilines: an alternative N-monoacylation reaction.
Theodorou V, et al.
ARKIVOC (Gainesville, FL, United States), 4, 11-23 (2014)
Tzvetomira Tzanova et al.
European journal of medicinal chemistry, 44(6), 2724-2730 (2008-10-28)
Considering that oxidative stress is strongly implicated in the toxicity of chemotherapy, much effort is focused on the research of diverse antioxidants as protective agents. An efficient synthesis of three novel benzophenones containing 1,3-thiazol moiety (6a-c) is described. Their antioxidant
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