404888
1-甲基-2-苯基吲哚
99%
别名:
NSC 63793
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关于此项目
经验公式（希尔记法）:
C15H13N
化学文摘社编号:
分子量:
207.27
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
222-618-1
MDL number:
产品名称
1-甲基-2-苯基吲哚, 99%
InChI key
SFWZZSXCWQTORH-UHFFFAOYSA-N
InChI
1S/C15H13N/c1-16-14-10-6-5-9-13(14)11-15(16)12-7-3-2-4-8-12/h2-11H,1H3
SMILES string
Cn1c(cc2ccccc12)-c3ccccc3
assay
99%
mp
98-100 °C (lit.)
functional group
phenyl
Quality Level
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Application
1-Methyl-2-phenylindole may be used in the following studies:
- The estimation of lipid peroxidation in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg.
- As chromogenic agent for the determination of estimation of malondialdehyde (MDA) production.
- Colorimetric assay of lipid peroxidation.
- Synthesis of 1-methyl-2-phenyl-3-(1,3,4-thiadiazol-2-yldiazenyl)-1H-indole.
- Synthesis of 3-(5-ethyl-1,3,4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole.
Reactant for preparation of:
Reactant for:
- Cyano indoles
- Difluorohydroxy indoles
Reactant for:
- Carboxylation of indoles
- Allylation of indoles
- Formylation of indoles
- Nitrosylation of indoles
General description
Reaction of 1-methyl-2-phenylindole with nitrogen dioxide or with nitrous acid (NaNO2-CH3COOH) in benzene has been studied. 1-Methyl-2-phenylindole is reported to react with malondialdehyde (MDA) and 4-hydroxyalkenals to afford a stable chromophore with intense maximal absorbance at 586nm.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
3-(5-Ethyl-1, 3, 4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole.
Seferoglu Z, et al.
Acta Crystallographica Section E, Structure Reports Online, 63(2), 568-570 (2007)
María Hernández-Trejo et al.
BMC immunology, 18(1), 3-3 (2017-01-08)
Oxidative damage present in obese/overweight mothers may lead to further oxidative stress conditions or inflammation in maternal and cord blood samples. Thirty-four pregnant women/newborn pairs were included in this study to assess the presence of oxidative stress biomarkers and their
Bread Leandro Gomes Cruz et al.
BMC cancer, 16, 58-58 (2016-02-06)
The occurrence of cancer during pregnancy merges two complex, poorly understood metabolic and hormonal conditions. This association can exacerbate the conditions of both the mother and the foetus. The branched-chain amino acid leucine enhances cellular activity, particularly by increasing protein
D Gérard-Monnier et al.
Chemical research in toxicology, 11(10), 1176-1183 (1998-10-20)
Under acidic and mild-temperature conditions, 1-methyl-2-phenylindole was found to react with malondialdehyde (MDA) and 4-hydroxyalkenals to yield a stable chromophore with intense maximal absorbance at 586 nm. The use of methanesulfonic acid results in optimal yields of chromophore produced from
Abraham Said Arellano Buendía et al.
International journal of molecular sciences, 19(10) (2018-10-14)
Diabetic nephropathy (DN) is presently the primary cause of chronic kidney disease and end-stage renal disease (ESRD). It has been suggested that inflammation and oxidative stress, in addition to or in concert with the metabolic changes, plays an important role
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