所有图片(1)
About This Item
线性分子式:
ClCO(CH2)8CO2CH3
CAS号:
分子量:
234.72
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
检测方案
97%
形式
liquid
折射率
n20/D 1.453 (lit.)
bp
159-160 °C/9 mmHg (lit.)
密度
1.052 g/mL at 25 °C (lit.)
SMILES字符串
COC(=O)CCCCCCCCC(Cl)=O
InChI
1S/C11H19ClO3/c1-15-11(14)9-7-5-3-2-4-6-8-10(12)13/h2-9H2,1H3
InChI key
ZUUUAAZQEMFVSN-UHFFFAOYSA-N
一般描述
Methyl 10-chloro-10-oxodecanoate (Methyl sebacoyl chloride, 10-Oxo-10-chlorodecanoic acid methyl ester) is a monomethyl ester of sebacinic acid.
应用
Methyl 10-chloro-10-oxodecanoate may be used in the preparation of the following:
- methyl 10-[2-methoxy-4-(3-trifluoromethyl-3H-diazirin-3-yl)phenyl]-10-oxodecanoate
- fluorescein-derivatives of Necrostatin-3
- methyl 10-oxo-10-(Pyren-3-yl)decanoate
警示用语：
Danger
危险声明
危险分类
Skin Corr. 1B
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Jenny L Maki et al.
Analytical biochemistry, 427(2), 164-174 (2012-06-05)
Necrotic cell death is prevalent in many different pathological disease states and in traumatic injury. Necroptosis is a form of necrosis that stems from specific signaling pathways, with the key regulator being receptor interacting protein 1 (RIP1), a serine/threonine kinase.
Effective synthesis of a carbon-linked diazirinyl fatty acid derivative via reduction of the carbonyl group to methylene with triethylsilane and trifluoroacetic acid.
Hashimoto M, et al.
Heterocycles, 59(1), 395-398 (2003)
Wallace Thompson et al.
Methods in molecular biology (Clifton, N.J.), 861, 149-158 (2012-03-20)
Attempts to characterize, quantify, and/or modulate the activity of the secreted phospholipase A(2) family of enzymes result from the diversity of physiological roles for which these enzymes have been implicated. The 1-palmitoyl-2-(10-pyrenedecanoyl)-phosphatidylglycerol (pyrenePG)-based fluorometric assay is a sensitive and readily
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