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质量水平
方案
98%
旋光性
[α]24/D −63.0°, c = 2.5 in methanol
mp
189 °C (dec.) (lit.)
官能团
carboxylic acid
phenyl
SMILES字符串
OC(=O)[C@@H]1CNC(=O)N1C(=O)OCc2ccccc2
InChI
1S/C12H12N2O5/c15-10(16)9-6-13-11(17)14(9)12(18)19-7-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,17)(H,15,16)/t9-/m0/s1
InChI key
AYSUEIZKNBGWGN-VIFPVBQESA-N
应用
Z-保护咪唑烷酮,用于连续 N-烷基化反应。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Journal of medicinal chemistry, 32(2), 289-297 (1989-02-01)
(4S)-1-Alkyl-3-[[N-(carboxyalkyl)amino]acyl]-2-oxoimidazolidine-4- carboxylic acid derivatives (3) were prepared by two methods. Their angiotensin converting enzyme (ACE) inhibitory activities and antihypertensive effects were evaluated, and the structure-activity relationships were discussed. The dicarboxylic acids 3a-n possessing S,S,S configuration showed potent in vitro ACE
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