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反应适用性
reaction type: solution phase peptide synthesis
reactivity: proton reactive
标记范围
3-4 mmol/g base loading
杂质
≤0.5 mmol/g Cl- (resin)
基质
crosslinked with 2% DVB
粒径
200-400 mesh
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一般描述
Dimethylaminomethyl-polystyrene, also known as benzyldimethylamine, is a polystyrene-supported resin crosslinked with divinylbenzene that is commonly used in solution phase peptide synthesis.
应用
Dimethylaminomethyl-polystyrene is used as a resin to synthesize hydrophobic dipeptides such as bis-phenylalanines that can be used in the study of peptide and protein aggregation. Additionally, it can also be utilized for neutralizing acidic solution in a reaction mixture due to its proton reactive nature.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Synthesis of bis-Phenylalanine, A Novel Eight-Membered Cyclic Dipeptide
BV Falcone
Synthetic Communications, 38, 411-418 (2008)
Synthesis and properties of new nucleotide analogues possessing squaramide moieties as new phosphate isosters
K Seio
European Journal of Organic Chemistry (2005)
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