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Merck
CN

391956

Sigma-Aldrich

二甲胺 溶液

2.0 M in THF

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别名:
N,N-Dimethylamine
线性分子式:
(CH3)2NH
CAS号:
分子量:
45.08
Beilstein:
605257
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22

形式

liquid

质量水平

浓度

1.90-2.20 M (by NaOH, titration)
2.0 M in THF

bp

~60 °C

密度

0.85 g/mL at 25 °C

SMILES字符串

CNC

InChI

1S/C2H7N/c1-3-2/h3H,1-2H3

InChI key

ROSDSFDQCJNGOL-UHFFFAOYSA-N

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应用

Dimethylamine solution (2M in THF) has been used in the synthesis of 2-dimethylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (bk-MDDMA) , a β-keto derivative of 3,4-methylenedioxyamphetamine (MDA) by reacting with 2-bromo-3′,4′-methylenedioxypropiophenone. It may also be used to synthesize organic intermediates such as dimethyl-(4-nitro-benzyl)-amine, dimethyl-(4-methyl-benzyl)-amine and 4-dimethylamino-but-2-enoic acid [4-(3,4-dichloro-6-fluoro-phenylamino)-quinazolin-6-yl]-amide.

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Central nervous system, Respiratory system

补充剂危害

WGK

WGK 1

闪点(°F)

-32.8 °F

闪点(°C)

-36 °C

个人防护装备

Eyeshields, Faceshields, Gloves

法规信息

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Discrimination and identification of regioisomeric ?-keto analogues of 3, 4-methylenedioxyamphetamines by gas chromatography-mass spectrometry.
Zaitsu K, et al.
Forensic Toxicology, 26(2), 45-51 (2008)
[11C]-dimethylamine as a labeling agent for PET biomarkers.
Jacobson O & Mishani E.
Applied Radiation and Isotopes, 66(2), 188-193 (2008)
C Mulder et al.
Journal of neural transmission (Vienna, Austria : 1996), 109(9), 1203-1208 (2002-08-31)
Nitric oxide (NO) may play a role in the pathophysiology of Alzheimer's disease (AD). Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase, is involved in regulation of NO production. Recently it has been reported that dimethylarginine dimethylaminohydrolase, an enzyme
L Lee et al.
Cancer research, 41(10), 3992-3994 (1981-10-01)
Using a method for nitrosamine analysis that gives high recovery values and that is free from artifactual synthesis of nitrosamines, we have shown that human feces do not contain volatile nitrosamines (detection limit, 0.1 to 0.5 microgram/kg). We also showed
Gerhild Zauner et al.
Biochimica et biophysica acta, 1820(9), 1420-1428 (2011-08-02)
Analysis of protein glycosylation is an important first step towards establishing the functions of glycans in health and disease. In contrast to N-glycans which are generally enzymatically released for analysis, there is no corresponding enzyme for O-glycan liberation. Therefore, O-glycans

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