所有图片(1)
别名:
4,4′-二甲氧基氯化三苯甲烷, DMT, DMT-Cl, 氯-4,4′-二甲氧基三苯基甲烷
经验公式（希尔记法）:
C21H19ClO2
CAS号:
分子量:
338.83
Beilstein:
2471942
EC 号:
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
检测方案
≥97.0% (HPLC)
mp
123-125 °C
SMILES字符串
COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3
InChI
1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
InChI key
JBWYRBLDOOOJEU-UHFFFAOYSA-N
基因信息
human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358)
rat ... Htr1a(24473) , Htr2a(29595)
应用
4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:
- For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.
- For 10 sulfhydryl group of oligonucleotide analogs as its DMTr thioether.
其他说明
有用的保护基团试剂；移除
警示用语：
Danger
危险分类
Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
2′-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine
Seela F and Ming X
Organic & Biomolecular Chemistry, 6(8), 1450-1461 (2008)
M.D. Matteucci et al.
Tetrahedron Letters, 81, 3243-3243 (1980)
M.P. Reddy et al.
Tetrahedron Letters, 28, 23-23 (1987)
Selective protection and deprotection procedures for thiol and hydroxyl groups
Huang Z and Benner SA
Synlett, 1993(01), 83-84 (1993)
V. Amarnath et al.
Chemical Reviews, 77, 183-183 (1977)
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