所有图片(1)
别名:
1,2,2-Trimethylpropyl methylphosphonate, 3,3-Dimethylbutan-2-yloxy(methyl)phosphinic acid, Mono(1,2,2-trimethylpropyl) methylphosphonate, O-Pinacolyl hydrogen methylphosphonate, O-Pinacolyl methylphosphonate, PMPA, Pinacolyl hydrogen methylphosphonate, [(3,3-Dimethylbutan-2-yl)oxy](methyl)phosphinic acid
线性分子式:
CH3P(O)(OH)OCH(CH3)C(CH3)3
推荐产品
质量水平
检测方案
97%
形式
liquid
折射率
n20/D 1.434 (lit.)
bp
96-106 °C/8 mmHg (lit.)
密度
1.032 g/mL at 25 °C (lit.)
SMILES字符串
CC(OP(C)(O)=O)C(C)(C)C
InChI
1S/C7H17O3P/c1-6(7(2,3)4)10-11(5,8)9/h6H,1-5H3,(H,8,9)
InChI key
BLALDUPQYCGKAG-UHFFFAOYSA-N
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警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Skin Irrit. 2
WGK
WGK 2
闪点(°F)
165.2 °F
闪点(°C)
74 °C
法规信息
监管及禁止进口产品
B Rosenwirth et al.
Journal of medical primatology, 28(4-5), 195-205 (1999-12-11)
Combination chemotherapy using potent anti-retroviral agents has led to significant advances in the clinical management of human immunodeficiency virus (HIV) disease. However, the emergence of multiple drug-resistant mutants, the high need for compliance to adhere to demanding drug-dosing schemes, and
Sung-Up Choi et al.
Journal of pharmaceutical sciences, 97(2), 931-943 (2007-06-05)
We have investigated the ability of lipid-indinavir particles composed of 3-to-1 lipid-drug molar ratio to encapsulate an aqueous marker calcein and anti-HIV drug (3)H-phosphonylmethoxypropyl-adenine (PMPA). Even at a high density of indinavir associated to lipid-indinavir nanoparticles, they form an enclosed
Harri Koskela et al.
Analytical chemistry, 90(14), 8495-8500 (2018-06-12)
The NMR-observable nuclei of the acidic and basic compounds experience pH dependence in chemical shift. This phenomenon can be exploited in NMR titrations to determine p Ka values of compounds, or in pH measurement of solutions using dedicated pH reference
Looking down the drug pipeline.
J Cadman
GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 12(3), 5-9 (2001-05-22)
Manisha Sathe et al.
The Analyst, 137(2), 406-413 (2011-11-19)
Immunoassay detection of O-pinacolyl methylphosphonic acid (PMPA) employing direct coating of N-2-aminoethyl-O-pinacolyl methylphosphonate (hapten B) on microtiter plates is reported. Coating was achieved by covalently linking hapten B to a glutaraldehyde (GA) polymer network directly bound to the polystyrene (PS)
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