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质量水平
方案
96%
表单
liquid
折射率
n20/D 1.45 (lit.)
密度
1.456 g/mL at 25 °C (lit.)
官能团
acyl chloride
ester
SMILES字符串
COC(=O)CCCCCCC(Cl)=O
InChI
1S/C9H15ClO3/c1-13-9(12)7-5-3-2-4-6-8(10)11/h2-7H2,1H3
InChI key
RKUPOLBFJIEWBZ-UHFFFAOYSA-N
警示用语:
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
A cyclodextrin-capped histone deacetylase inhibitor.
Biochemical Medicine, 23(11), 3346-3348 (2013)
ACS medicinal chemistry letters, 2(5), 358-362 (2011-05-17)
N(1)-Hydroxy-N(8)-ferrocenyloctanediamide, JAHA (7), an organometallic analogue of SAHA containing a ferrocenyl group as a phenyl bioisostere, displays nanomolar inhibition of class I HDACs, excellent selectivity over class IIa HDACs, and anticancer action in intact cells (IC(50) = 2.4 μM, MCF7
Analytical and bioanalytical chemistry, 394(6), 1679-1685 (2009-06-02)
A fluorescent assay for the evaluation of inhibitors of fatty acid amide hydrolase (FAAH) is described. Microsomes from rat brain served as enzyme source. N-(2-Hydroxyethyl)-4-pyren-1-ylbutanamide was designed and synthesized as novel fluorogenic substrate. For substrate solubilization, Triton X-100 was employed.
Synthesis of 1-Aminocyclopropyl-Pentanoic and-Heptanoic Acid Derivatives.
Letters in Organic Chemistry, 5(5), 328-331 (2008)
Synthesis and properties of PI polyamide?SAHA conjugate.
Tetrahedron Letters, 50(52), 7288-7292 (2009)
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