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Merck
CN

379700

Sigma-Aldrich

10-羟基癸酸

technical grade

别名:

NSC 15139

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About This Item

线性分子式:
HO(CH2)9CO2H
CAS号:
分子量:
188.26
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

等级

technical grade

表单

solid

杂质

<15% intermolecular dilactone

mp

75-77 °C (lit.)

官能团

carboxylic acid
hydroxyl

SMILES字符串

OCCCCCCCCCC(O)=O

InChI

1S/C10H20O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h11H,1-9H2,(H,12,13)

InChI key

YJCJVMMDTBEITC-UHFFFAOYSA-N

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一般描述

10-羟基癸酸 (10-HDA) 是羟基--2-癸烯酸 (10H2DA) 的饱和脂肪酸。其分子有两个官能团(-OH 和-COOH)。据报告,它可以阻止脂多糖诱导的小鼠巨噬细胞 NO 的产生。10-HDA 是从蜜蜂(蜂)的蜂王浆中提取的,具有雌激素操作。 它与聚乙二醇修饰的脂肪酶在透明的苯溶液中通过形成酯键聚合。

应用

10-羟基癸酸适用于研究 Novozym 435 催化的顺式-9,10-环氧-18-羟基十八碳酸的缩聚及其与相应的的 10-羟基癸酸聚合的比较。
反应物参与到:
  • 丙烯酰胺与丙烯酰氧基癸酸钠共聚物的合成
  • 宏观内酯化制备 Sansalvamide A
  • 角质酶催化缩聚反应链长选择性的研究
  • 钌催化酯化,然后大环化
  • 酸酐和酯的合成

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Kazu-Michi Suzuki et al.
Evidence-based complementary and alternative medicine : eCAM, 5(3), 295-302 (2008-10-03)
We have previously reported that royal jelly (RJ) from honeybees (Apis mellifera) has weak estrogenic activity mediated by interaction with estrogen receptors that leads to changes in gene expression and cell proliferation. In this study, we isolated four compounds from
Keita Takahashi et al.
Biomedical research (Tokyo, Japan), 34(4), 205-214 (2013-09-03)
Toll-like receptors (TLRs) play a critical role in innate immunity by recognizing pathogen-associated molecular patterns. Various environmental materials including lipids may affect TLR signaling and modulate innate immune responses. We previously reported that 10-hydroxy-trans-2-decenoic acid (10H2DA) inhibits lipopolysaccharide (LPS)-induced interleukin
Polymerization of 10-hydroxydecanoic acid in benzene with polyethylene glycol-modified lipase.
Ajima A, et al.
Biotechnology Letters, 7(5), 303-306 (1985)
Maroula G Kokotou et al.
Metabolites, 10(1) (2020-01-23)
The lipidome of royal jelly (RJ) consists of medium-chained (8-12 carbon atoms) free fatty acids. We present herein a liquid chromatography-high resolution mass spectrometry (HRMS) method that permits the determination of RJ fatty acids and at the same time the
Martin T Gaugg et al.
Journal of breath research, 11(4), 046004-046004 (2017-09-14)
We explore whether real-time breath analysis by high resolution mass spectrometry is suitable to monitor changes at the metabolic level due to inhaling bronchodilator medication. We compared the breath levels of metabolites in a group of patients (n = 50) at baseline

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