所有图片(1)
About This Item
经验公式（希尔记法）:
C7H9NO2
CAS号:
分子量:
139.15
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
检测方案
98%
形式
powder
mp
272-275 °C (lit.)
SMILES字符串
CN1C=CC(=O)C(O)=C1C
InChI
1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3
InChI key
TZXKOCQBRNJULO-UHFFFAOYSA-N
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一般描述
3-羟基-1,2-二甲基-4(1H)-吡啶酮（Hdpp，去铁酮）是一种羟基酮衍生物。 它在酸性水溶液中与铀酰盐[UO2(NO3)2]反应，得到单核复合物（[UO2(dpp)(Hdpp)2(H2O)]ClO4）。 已通过X射线研究分析了这些复合物的结构和几何结构。
应用
3-羟基-1,2-二甲基-4(1H)-吡啶酮（OH-吡啶酮）可用于杀菌试验。它已被用作羟基酮螯合剂，并且已经评估了其对人口腔正常和肿瘤细胞的细胞毒作用。
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Etheresia Pretorius et al.
Toxicology mechanisms and methods, 23(5), 352-359 (2013-01-03)
Inflammatory diseases associated with iron overload are characterized by a changed coagulation profile, where there is a persistent presence of fibrin-like material of dense-matted deposits (DMDs). It is believed that one source of such material is a result of the
Chryssoula Drouza et al.
Inorganic chemistry, 43(26), 8336-8345 (2004-12-21)
Reaction of [UO(2)(NO(3))(2)] with the hydroxy ketones 3-hydroxy-2-methyl-4-pyrone (Hma) and 3-hydroxy-1,2-dimethyl-4(1H)-pyridone (Hdpp) in aqueous acidic solutions (pH approximately 3) yields the compounds [UO(2)(ma)(2)(H(2)O)].H(2)O (1.H(2)O) and [UO(2)(dpp)(Hdpp)(2)(H(2)O)]ClO(4) (2), respectively. X-ray diffraction shows that the geometry around the metal ion in both
Jaroslav Cermak et al.
Leukemia research, 37(12), 1612-1615 (2013-08-14)
One hundred thirteen patients with myelodysplastic syndromes (MDS) with <10% of bone marrow blasts received either deferiprone in a daily dose of 40-90 mg/kg (48 patients) or deferasirox in a daily dose of 10-40 mg/kg (65 patients). Median duration of
Raffaella Origa et al.
British journal of haematology, 163(3), 400-403 (2013-09-17)
This study aimed to verify the impact of heart magnetic resonance imaging on chelation choices and patient compliance in a single-institution cohort as well as its predictive value for heart failure and arrhythmias. Abnormal cardiac T2* values determined changes in
Carole Peyssonnaux et al.
The Journal of clinical investigation, 115(7), 1806-1815 (2005-07-12)
Hypoxia is a characteristic feature of the tissue microenvironment during bacterial infection. Here we report on our use of conditional gene targeting to examine the contribution of hypoxia-inducible factor 1, alpha subunit (HIF-1alpha) to myeloid cell innate immune function. HIF-1alpha
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