所有图片(1)
About This Item
线性分子式:
C6H11N=C=NC6H11
CAS号:
分子量:
206.33
MDL编号:
UNSPSC代码:
12352111
PubChem化学物质编号:
NACRES:
NA.22
product name
N,N′-二环己基碳二亚胺 溶液, 1.0 M in methylene chloride
形式
liquid
质量水平
反应适用性
reaction type: Coupling Reactions
浓度
1.0 M in methylene chloride
密度
1.247 g/mL at 25 °C
应用
peptide synthesis
SMILES字符串
C1CCC(CC1)N=C=NC2CCCCC2
InChI
1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2
InChI key
QOSSAOTZNIDXMA-UHFFFAOYSA-N
基因信息
human ... EPHX2(2053)
mouse ... Ephx2(13850)
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相关类别
应用
DCC（ N ， N ′）-二环己基碳二亚胺）主要用于介导肽偶联 ，也可活化羧酸进行酯化。
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官
Central nervous system
WGK
WGK 3
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Liposomes containing alkylated methotrexate analogues for phospholipase A 2 mediated tumor targeted drug delivery.
Kaasgaard T, et al.
Chemistry and Physics of Lipids, 157(2), 94-103 (2009)
Effects of amounts of additives on peptide coupling mediated by a water?soluble carbodiimide in alcohols.
Nozaki S.
The Journal of Peptide Research, 54(2), 162-167 (1999)
Kenji Mizutani et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(33), 13474-13479 (2011-08-05)
The prokaryotic V-ATPase of Enterococcus hirae, closely related to the eukaryotic enzymes, provides a unique opportunity to study the ion-translocation mechanism because it transports Na(+), which can be detected by radioisotope (22Na(+)) experiments and X-ray crystallography. In this study, we
Masashi Toei et al.
The Journal of biological chemistry, 288(36), 25717-25726 (2013-07-31)
N,N-Dicyclohexylcarbodiimide (DCCD) is a classical inhibitor of the F0F1-ATP synthase (F0F1), which covalently binds to the highly conserved carboxylic acid of the proteolipid subunit (c subunit) in F0. Although it is well known that DCCD modification of the c subunit
Denys Pogoryelov et al.
Nature chemical biology, 6(12), 891-899 (2010-10-26)
The microscopic mechanism of coupled c-ring rotation and ion translocation in F(1)F(o)-ATP synthases is unknown. Here we present conclusive evidence supporting the notion that the ability of c-rings to rotate within the F(o) complex derives from the interplay between the
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