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Merck
CN

377430

Sigma-Aldrich

异硫氰酸烯丙酯

95%

别名:

AITC, 芥子油

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About This Item

线性分子式:
CH2=CHCH2NCS
CAS号:
分子量:
99.15
Beilstein:
773748
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

95%

表单

liquid

包含

BHT as stabilizer

折射率

n20/D 1.529 (lit.)

沸点

150 °C (lit.)

mp

−80 °C (lit.)

密度

1.013 g/mL at 25 °C (lit.)

官能团

amine
isothiocyanate

储存温度

2-8°C

SMILES字符串

C=CCN=C=S

InChI

1S/C4H5NS/c1-2-3-5-4-6/h2H,1,3H2

InChI key

ZOJBYZNEUISWFT-UHFFFAOYSA-N

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应用

Allyl isothiocyanate (AITC) was suitable for use in the following studies:
  • Quantitation of the N-acetylcysteine conjugate of AITC in human urine after ingestion of mustard.
  • Evaluation of the fungitoxic activity of AITC vapour on Penicillium expansum on pears, particularly on a thiabendazole (TBZ)-resistant P. expansum strain in vivo, to verify whether AITC treatment could be a substitute for TBZ.
  • Study of the induction of acetylation of histone in mouse erythroleukemia cells by some organosulfur compounds.

生化/生理作用

它是十字花科蔬菜的天然成分。

警示用语:

Danger

危险分类

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

113.0 °F - closed cup

闪点(°C)

45 °C - closed cup

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Ying Li et al.
Journal of colloid and interface science, 438, 130-137 (2014-12-03)
Allyl isothiocyanate (AITC), an organosulfur compound in cruciferous vegetables, is a natural antimicrobial and potential chemopreventive agent. However, the instability of AITC in aqueous systems restrains its applications. In this study, oil-in-water AITC nanoemulsion was prepared by the emulsion inversion
Francielle de Vargas Pinheiro et al.
European journal of pharmacology, 747, 105-113 (2014-12-17)
Sympathetic fibres maintain some forms of neuropathic pain, but the underlying mechanisms are poorly understood. Therefore, this study investigated the possible involvement of transient receptor potential ankyrin 1 (TRPA1) and the role of the sympathetic nervous system (involved in sympathetically
Jill M Recla et al.
Pain, 160(8), 1740-1753 (2019-07-25)
Identification of genetic variants that influence susceptibility to pain is key to identifying molecular mechanisms and targets for effective and safe therapeutic alternatives to opioids. To identify genes and variants associated with persistent pain, we measured late-phase response to formalin
Chang Liu et al.
Neuron, 109(2), 273-284 (2020-11-06)
The TRPA1 ion channel is activated by electrophilic compounds through the covalent modification of intracellular cysteine residues. How non-covalent agonists activate the channel and whether covalent and non-covalent agonists elicit the same physiological responses are not understood. Here, we report
Antifungal vapour-phase activity of allyl-isothiocyanate against Penicillium expansum on pears.
Mari M, et al.
Plant Pathology, 51(2), 231-236 (2002)

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