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![N-[(1R,2R)-2-(1-哌啶基）环己基]-N′-[4-（三氟甲基）苯基]四酰胺 95%](/deepweb/assets/sigmaaldrich/product/structures/238/480/7149c9c0-8769-418a-a96c-77c15dd50cd0/640/7149c9c0-8769-418a-a96c-77c15dd50cd0.png)
质量水平
检测方案
99%
形式
solid
mp
55-57 °C (lit.)
储存温度
2-8°C
SMILES字符串
COC1=C(OC)C(=O)C1=O
InChI
1S/C6H6O4/c1-9-5-3(7)4(8)6(5)10-2/h1-2H3
InChI key
SZBNZTGCAMLMJY-UHFFFAOYSA-N
一般描述
3,4-二甲氧基-3-环丁烯-1,2-二酮（方酸二甲酯）是环丁烯衍生物。它与羟胺衍生物反应得到 3-羟氨基-4-甲氧基-3-环丁烯-1,2-二酮。
应用
3,4-二甲氧基-3-环丁烯-1,2-二酮（方酸二甲酯）可用于合成以下化合物：
- 手性方胺，吲哚类 Friedel-Crafts 反应的高对映选择性催化剂
- 3-（羟氨基）-4-甲氧基-3-环丁烯-1,2-二酮
- O-SP-核心抗原的方形衍生物
- Ogawa O-SP-核心抗原的方酸甲酯衍生物
- o-醌二甲烷
- 苯环丁烯
- 醌类
警示用语：
Danger
危险声明
危险分类
Resp. Sens. 1 - Skin Sens. 1
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Yong Qian et al.
Chemical communications (Cambridge, England), 46(17), 3004-3006 (2010-04-14)
Chiral squaramides are highly enantioselective catalysts for Friedel-Crafts reaction of indoles with N-tosyl imines, affording 3-indolyl methanamine products in 85-96% yields and 84-96% ees.
The Journal of Organic Chemistry, 59, 3284-3284 (1994)
Mohammad Murshid Alam et al.
PLoS neglected tropical diseases, 8(2), e2683-e2683 (2014-02-12)
Protective immunity against cholera is serogroup specific. Serogroup specificity in Vibrio cholerae is determined by the O-specific polysaccharide (OSP) of lipopolysaccharide (LPS). Generally, polysaccharides are poorly immunogenic, especially in young children. Here we report the evaluation in mice of a
Hydroxylamin-Derivate der Quadratsaure.
Zinner G, et al.
Arch. Pharm. (Weinheim), 318(11), 977-983 (1985)
Kerriann K Badal et al.
Cell reports, 26(3), 507-517 (2019-01-17)
Mechanisms that regulate the bi-directional transport of mitochondria in neurons for maintaining functional synaptic connections are poorly understood. Here, we show that in the pre-synaptic sensory neurons of the Aplysia gill withdrawal reflex, the formation of functional synapses leads to
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