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Merck
CN

369055

Sigma-Aldrich

2-溴-4-氟苯胺

97%

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线性分子式:
BrC6H3(F)NH2
CAS号:
分子量:
190.01
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

检测方案

97%

形式

solid

折射率

n20/D 1.583 (lit.)

bp

221 °C (lit.)

密度

1.67 g/mL at 25 °C (lit.)

SMILES字符串

Nc1ccc(F)cc1Br

InChI

1S/C6H5BrFN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2

InChI key

YLMFXCIATJJKQL-UHFFFAOYSA-N

一般描述

2-Bromo-4-fluoroaniline is an aryl fluorinated building block.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

219.2 °F

闪点(°C)

104 °C

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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An efficient synthesis of enantiomerically pure aromatic-fused N-containing heterocycles from common chiral aziridines.
Chan Kim J, et al.
Tetrahedron, 66(40), 8108-8114 (2010)
Synthesis of fluorescent tetracyclic lactams by a ?one pot? three steps palladium-catalyzed borylation, Suzuki coupling (BSC) and lactamization: DNA and polynucleotides binding studies.
Queiroz M-JRP, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 190(1), 45-52 (2007)
Fatma K Abdel-Wadood et al.
Archiv der Pharmazie, 347(2), 142-152 (2014-01-01)
2-Bromo-4-fluoroaniline (1) was condensed with ethyl 2-cyano-3-ethoxyacrylate (2) in ethanol to afford 3, which upon refluxing in paraffin oil at 250°C gave 8-bromo-3-cyano-6-fluoroquinoline-4(1H)-one (4). Then, compound 4 was taken as a versatile building block that allows the synthesis of thieno[3,2-c]quinoline

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