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Merck
CN

367931

Sigma-Aldrich

2-溴-4-氟苯甲酸

97%

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About This Item

线性分子式:
BrC6H3(F)CO2H
CAS号:
分子量:
219.01
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

97%

表单

solid

mp

172-176 °C (lit.)

SMILES字符串

OC(=O)c1ccc(F)cc1Br

InChI

1S/C7H4BrFO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,(H,10,11)

InChI key

RRKPMLZRLKTDQV-UHFFFAOYSA-N

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一般描述

Amination of 2-bromo-4-fluorobenzoic acid with aniline is reported to yield N-phenyl-4-fluoro-anthranilic acid.

应用

2-Bromo-4-fluorobenzoic acid may be used in the synthesis of:
  • 3-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one
  • 2-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one
  • 2-((2-carboxy-5-fluorophenyl)amino)-3-methoxybenzoic acid
  • 2-bromo-4-fluorobenzamide

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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Lauren R Donaldson et al.
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Kopicova Z, et al.
Collection of Czechoslovak Chemical Communications, 40(11), 3519-3529 (1975)
Bernd Dörner et al.
Bioorganic & medicinal chemistry, 19(7), 2190-2198 (2011-03-23)
Aim of this study was to label the potent dual P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor elacridar (1) with (18)F to provide a positron emission tomography (PET) radiotracer to visualize Pgp and BCRP. A series of new
Christian Wolf et al.
The Journal of organic chemistry, 71(8), 3270-3273 (2006-04-08)
A chemo- and regioselective copper-catalyzed cross-coupling procedure for amination of 2-bromobenzoic acids is described. The method eliminates the need for acid protection and produces N-aryl and N-alkyl anthranilic acid derivatives in up to 99% yield. N-(1-Pyrene)anthranilic acid has been employed
Fu-Xiang Wang et al.
Developmental cell, 54(6), 742-757 (2020-08-07)
Plant somatic embryogenesis refers to a phenomenon where embryos develop from somatic cells in the absence of fertilization. Previous studies have revealed that the phytohormone auxin plays a crucial role in somatic embryogenesis by inducing a cell totipotent state, although

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