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![5-Iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/204/107/add11006-5cb7-4629-82af-1c7ce949f54f/640/add11006-5cb7-4629-82af-1c7ce949f54f.png)
方案
98%
mp
78-80 °C (lit.)
SMILES字符串
O=S(=O)(c1ccccc1)n2ccc3ccccc23
InChI
1S/C14H11NO2S/c16-18(17,13-7-2-1-3-8-13)15-11-10-12-6-4-5-9-14(12)15/h1-11H
InChI key
VDWLCYCWLIKWBV-UHFFFAOYSA-N
应用
1-(Phenylsulfonyl)indole may be used in the preparation of 2-acyl-1-(phenylsulfonyl)indoles. It may be used in the synthesis of starting reagent required for the synthesis of the potentially useful intermediate, 1-(phenylsulfonyl)indol-3-yl trifluoromethanesulfonate (triflate).
Reactant for preparation of:
- Antiplasmodial agents
- Antifungal agents
- Anti HIV-1 agents
- Agonists of the histamine H4 receptor
- Antibacterial agents
- Camalexin analogs
- CDK inhibitors and cytotoxic agents
- Histone Deacetylase inhibitors
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Synthesis of 1-(phenylsulfonyl) indol-3-YL trifluoromethanesulfonate.
Conway SC and Gribble GW.
Heterocycles, 30(1), 627-633 (1990)
A direct lithiation route to 2-acyl-1-(phenylsulfonyl) indoles.
Jiang J and Gribble GW.
Synthetic Communications, 32(13), 2035-2040 (2002)
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