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Merck
CN

363340

Sigma-Aldrich

N-乙酰基半胱胺

95%

别名:

N-(2-Mercaptoethyl)acetamide

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About This Item

线性分子式:
CH3CONHCH2CH2SH
CAS号:
分子量:
119.19
MDL编号:
UNSPSC代码:
12352100
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

95%

表单

liquid

折射率

n20/D 1.511 (lit.)

沸点

138-140 °C/7 mmHg (lit.)

mp

6-7 °C (lit.)

密度

1.121 g/mL at 25 °C (lit.)

官能团

amide
thiol

SMILES字符串

CC(=O)NCCS

InChI

1S/C4H9NOS/c1-4(6)5-2-3-7/h7H,2-3H2,1H3,(H,5,6)

InChI key

AXFZADXWLMXITO-UHFFFAOYSA-N

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相关类别

一般描述

N-Acetylcysteamine, also known as N-(2-Mercaptoethyl) acetamide, is a derivative of cysteamine, that is commonly used as a building block for the synthesis of alkylated thiol and thioesters via esterification.

应用

N-乙酰半胱氨酸可作为结构单元用于合成:
  • N







  • -乙酰半胱胺(SNAC)硫酯,通过在1,1′-羰二咪唑(CDI)参与下与多种酸衍生物反应。      
  • 噻吩并[2,3-c]吡咯衍生物,通过2-乙酰基-3-噻吩甲醛和各种胺的三组分反应。
  • 碳青霉烯是一类beta-内酰胺类抗生素。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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分析证书(COA)

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Isolation, properties, and regulation of a mitochondrial acyl coenzyme A thioesterase from pig heart.
K Y Lee et al.
The Journal of biological chemistry, 254(11), 4516-4523 (1979-06-10)
N Singh et al.
Biochemical and biophysical research communications, 131(2), 786-792 (1985-09-16)
The acetyl transacylase activity of the fatty acid synthase from yeast has been investigated using p-nitrophenylthiol acetate. The chromophoric nature of the nitrophenylthiol moiety affords a convenient spectrophotometric assay for the transacylase function as well as a means to investigate
Magoichi Sako et al.
The Journal of organic chemistry, 63(20), 6947-6951 (2001-10-24)
4H-[1,2,5]Oxadiazolo[3,4-d]pyrimidine-5,7-dione 1-oxides (2) are conveniently prepared in high yields by the oxidative intramolecular cyclization of 6-amino-5-nitro-1H-pyrimidine-2,4-diones (1) employing iodosylbenzene diacetate as an oxidant in the presence of lithium hydride. The generation of nitric oxide (NO) and NO-related species from 2
Micah J Bodner et al.
Organic letters, 11(16), 3606-3609 (2009-07-21)
Efficient syntheses of N-acetyl thienamycin and epithienamycin A in their readily deprotected form are reported where three contiguous stereocenters are established in a single catalytic asymmetric azetidinone-forming reaction. These examples are a template for synthesizing C-5/C-6 cis or trans carbapenems
Cell cycle arrest and apoptosis induction by an anticancer chalcone epoxide
Haiyong H, et al
Archives of Pharmacal Research, 343, 429-439 (2010)

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