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一般描述
N-Acetylcysteamine, also known as N-(2-Mercaptoethyl) acetamide, is a derivative of cysteamine, that is commonly used as a building block for the synthesis of alkylated thiol and thioesters via esterification.
应用
N-乙酰半胱氨酸可作为结构单元用于合成:
- N
- -乙酰半胱胺(SNAC)硫酯,通过在1,1′-羰二咪唑(CDI)参与下与多种酸衍生物反应。
- 噻吩并[2,3-c]吡咯衍生物,通过2-乙酰基-3-噻吩甲醛和各种胺的三组分反应。
- 碳青霉烯是一类beta-内酰胺类抗生素。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Isolation, properties, and regulation of a mitochondrial acyl coenzyme A thioesterase from pig heart.
The Journal of biological chemistry, 254(11), 4516-4523 (1979-06-10)
Biochemical and biophysical research communications, 131(2), 786-792 (1985-09-16)
The acetyl transacylase activity of the fatty acid synthase from yeast has been investigated using p-nitrophenylthiol acetate. The chromophoric nature of the nitrophenylthiol moiety affords a convenient spectrophotometric assay for the transacylase function as well as a means to investigate
The Journal of organic chemistry, 63(20), 6947-6951 (2001-10-24)
4H-[1,2,5]Oxadiazolo[3,4-d]pyrimidine-5,7-dione 1-oxides (2) are conveniently prepared in high yields by the oxidative intramolecular cyclization of 6-amino-5-nitro-1H-pyrimidine-2,4-diones (1) employing iodosylbenzene diacetate as an oxidant in the presence of lithium hydride. The generation of nitric oxide (NO) and NO-related species from 2
Organic letters, 11(16), 3606-3609 (2009-07-21)
Efficient syntheses of N-acetyl thienamycin and epithienamycin A in their readily deprotected form are reported where three contiguous stereocenters are established in a single catalytic asymmetric azetidinone-forming reaction. These examples are a template for synthesizing C-5/C-6 cis or trans carbapenems
Cell cycle arrest and apoptosis induction by an anticancer chalcone epoxide
Archives of Pharmacal Research, 343, 429-439 (2010)
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