推荐产品
检测方案
97%
mp
229-231 °C (dec.) (lit.)
SMILES字符串
OC(=O)CCc1nc2ccccc2[nH]1
InChI
1S/C10H10N2O2/c13-10(14)6-5-9-11-7-3-1-2-4-8(7)12-9/h1-4H,5-6H2,(H,11,12)(H,13,14)
InChI key
XYWJNTOURDMTPI-UHFFFAOYSA-N
一般描述
2-Benzimidazolepropionic acid is a 2-(4-thiazolyl)benzimidazole analog. 2-Benzimidazolepropionic acid is a 2-substituted benzimidazole ligand and its dissociation constant has been evaluated. 2-Benzimidazolepropionic acid is reported to possess active antimarial activity.
应用
2-Benzimidazolepropionic acid is suitable reagent for use in the method of generation of monoclonal antibodies against very small drug hapten, 5-benzimidazolecarboxylic acid by in vivo immunisation method and an in vitro immunisation procedure. It may be used in the synthesis of cytidine derivatives.
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
W Kuźmierkiewicz et al.
Die Pharmazie, 40(7), 462-464 (1985-07-01)
Condensation reactions of 3-(1H-benzimidazole-2)propanoic acid (procodazol) with aromatic aldehydes were carried out resulting in lactam and acid derivatives. Basing on the spectral studies (MS, NMR) it was found that in the reaction the hydrogen atoms of the 3-methylene group of
Christine M Crane et al.
ChemMedChem, 3(1), 91-101 (2007-11-23)
The enzymes of the non-mevalonate pathway for isoprenoid biosynthesis are attractive targets for the development of novel drugs against malaria and tuberculosis. This pathway is used exclusively by the corresponding pathogens, but not by humans. A series of water-soluble, cytidine-based
Ghassan Abu Sheikha et al.
Chemical & pharmaceutical bulletin, 66(4), 423-426 (2018-04-03)
Hyperlipidemia is known as an elevation of plasma lipid components. It contributes significantly to atherosclerosis which is one of the most important causative factors in cardiovascular diseases. Agents that cause a dramatic decrease in serum lipid levels are of great
E Moran et al.
Journal of immunological methods, 271(1-2), 65-75 (2002-11-26)
Drug-specific monoclonal antibodies (MAbs) were produced against the very small drug hapten (162.15 Da), 5-benzimidazolecarboxylic acid, an analogue of 2-(4-Thiazolyl)benzimidazole (TBZ) but lacking the thiol group. TBZ is widely used as a broad-spectrum anthelmintic in various animal species and humans
G Martinez et al.
Medicina cutanea ibero-latino-americana, 16(3), 197-200 (1988-01-01)
We are commenting on a case of cutaneous mycobacteriosis (M. chelonei) in an asthmatic 60-year-old patient under continuous steroid treatment, who months after an accidental trauma on his hand, developed painful papular lesions, located over the trauma scar, and on
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