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Merck
CN

361860

99.8 atom % D

别名:

D2

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关于此项目

线性分子式:
D2
化学文摘社编号:
分子量:
4.03
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:
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产品名称

氘, 99.8 atom % D

InChI key

UFHFLCQGNIYNRP-VVKOMZTBSA-N

SMILES string

[2H][2H]

InChI

1S/H2/h1H/i1+1D

vapor density

0.07 (vs air)

isotopic purity

99.8 atom % D

assay

99.995% (CP)

form

gas (compressed)

bp

-249.5 °C (lit.)

density

0.169 g/mL at -250.9 °C (liq)(lit.)
0.165 g/L at 25 °C (gas)

Quality Level

application(s)

electronics

mass shift

M+2

storage temp.

room temp

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Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
带 CGA 110/180 铜质阀的气阀瓶
All gas volumes are quoted at Normal Temperature and Pressure (NTP) and not at Standard Temperature and Pressure (STP).

Other Notes

推荐使用不锈钢控制阀 Z146951、Z187224 或不锈钢调节器 Z148504 和 Z148512 中的任意一种。

Application

- Deuterium labeling for metabolic and pharmacokinetic studies
- synthesis of deuterated reference standards
- Isotope effect investigations in reaction mechanisms
- Chemical synthesis of labeled compounds

Features and Benefits

Features
- High deuterium content for effective labeling
- Versatile application in drug development
- Enhances metabolic stability of compounds
- Supports innovative pharmaceutical research

Benefits
- Accelerates drug discoverytimelines
- Improves the accuracy of pharmacokinetic studies
- Increases the robustness of formulations
- Supports the development of next-generation therapies

General description

Deuterium 99.8 atom % D is a high-purity isotope product with a unique chemical profile that belongs to the class of isotopes. Produced by Sigma-Aldrich, we are committed to providing quality isotope products and a reliable supply chain. Available in industrial and pre-pack quantities.

pictograms

FlameGas cylinder

signalword

Danger

hcodes

Hazard Classifications

Flam. Gas 1A - Press. Gas Compr. Gas

存储类别

2A - Gases

wgk

nwg

flash_point_f

<-238.0 °F - closed cup

flash_point_c

< -150 °C - closed cup

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Martin Byrdin et al.
Biochimica et biophysica acta, 1655(1-3), 64-70 (2004-04-22)
We review our work on electron transfer and proton dynamics during photoactivation in DNA photolyase from E. coli and discuss a recent theoretical study on this issue. In addition, we present unpublished data on the charge recombination between the fully
Michael Landreh et al.
The FEBS journal, 278(20), 3815-3821 (2011-06-15)
The study of protein structure and function has evolved to become a leading discipline in the biophysical sciences. Although it is not yet possible to determine 3D protein structures from MS data alone, multiple MS-based techniques can be combined to
Srinath Krishnamurthy et al.
Biochimica et biophysica acta, 1834(6), 1215-1221 (2013-03-19)
cAMP signaling is a fundamental cellular process necessary for mediating responses to hormonal stimuli. In contrast to cAMP-dependent activation of protein kinase A (PKA), an important cellular target, far less is known on termination in cAMP signaling, specifically how phosphodiesterases
Ying Zhang et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(36), 14604-14609 (2013-08-21)
Probing the conformational changes of amyloid beta (Aβ) peptide aggregation is challenging owing to the vast heterogeneity of the resulting soluble aggregates. To investigate the formation of these aggregates in solution, we designed an MS-based biophysical approach and applied it
Masaru Hoshino et al.
Biochimica et biophysica acta, 1768(8), 1886-1899 (2007-05-15)
A general method to analyze the structure of a supramolecular complex of amyloid fibrils at amino acid residue resolution has been developed. This method combines the NMR-detected hydrogen/deuterium (H/D) exchange technique to detect hydrogen-bonded amide groups and the ability of

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